Remodeling the Th1 polarized systemic environment contributes to neurogenesis and cognitive function via the Wnt7a pathway in neonatal mice
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2017.03.002
Abstract: HIGHLIGHTSBCG‐serum induces a Th1 polarized systemic environment in neonatal mice.Remodeling Th1 polarized systemic environment improves hippocampal neurogenesis and cognitive function.Remodeling Th1 polarized systemic environment activates canonical Wnt7a/&bgr;‐catenin signaling pathway in hippocampus.Remodeling Th1 polarized systemic environment… read more here.
Keywords: polarized systemic; serum; th1 polarized; mice ... See more keywords
Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12121379
Abstract: Dengue virus (DENV), an arbovirus, strongly activates mast cells (MCs), which are key immune cells for pathogen immune surveillance. In animal models, MCs promote clearance of local peripheral DENV infections but, conversely, also promote pathological… read more here.
Keywords: dengue virus; denv; mast cells; permeability ... See more keywords
CCL28 Enhances HSV-2 gB-Specific Th1-Polarized Immune Responses against Lethal Vaginal Challenge in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10081291
Abstract: Plasmid DNA (pDNA) represents a promising “genetic vaccine platform” capable of overcoming major histocompatibility complex barriers. We previously demonstrated that low-to-moderate doses of mucosae-associated epithelial chemokine (MEC or CCL28) as an immunomodulatory adjuvant can trigger… read more here.
Keywords: th1 polarized; immune responses; hsv specific; ccr10 ... See more keywords