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   Articles with "th1 th17" as a keyword



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Human dendritic cells activated with MV130 induce Th1, Th17 and IL‐10 responses via RIPK2 and MyD88 signalling pathways

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recommendations! Published in 2018 at "European Journal of Immunology"

DOI: 10.1002/eji.201747024

Abstract: Recurrent respiratory tract infections (RRTIs) are the first leading cause of community‐ and nosocomial‐acquired infections. Antibiotics remain the mainstay of treatment, enhancing the potential to develop antibiotic resistances. Therefore, the development of new alternative approaches… read more here.

Keywords: signalling pathways; responses via; dendritic cells; th1 th17 ... See more keywords
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T-lymphocyte-derived enkephalins reduce Th1/Th17 colitis and associated pain in mice

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recommendations! Published in 2017 at "Journal of Gastroenterology"

DOI: 10.1007/s00535-017-1341-2

Abstract: BackgroundEndogenous opioids, including enkephalins, are fundamental regulators of pain. In inflammatory conditions, the local release of opioids by leukocytes at the inflammatory site inhibits nociceptor firing, thereby inducing analgesia. Accordingly, in chronic intestinal Th1/Th17-associated inflammation,… read more here.

Keywords: derived enkephalins; inflammation; colitis; th1 th17 ... See more keywords
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Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.

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recommendations! Published in 2022 at "Cellular immunology"

DOI: 10.1016/j.cellimm.2022.104500

Abstract: Multiple sclerosis (MS) was one of the major conditions causing neurological dysfunction and was an incurable progressive central nervous system disease. Experimental autoimmune encephalomyelitis (EAE) was the most commonly used experimental model of MS. Artemisinin… read more here.

Keywords: eae; tpn10466; th17 differentiation; disease ... See more keywords
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Unique glandular ex-vivo Th1 and Th17 receptor motifs in Sjögren's syndrome patients using single-cell analysis.

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recommendations! Published in 2018 at "Clinical immunology"

DOI: 10.1016/j.clim.2018.04.009

Abstract: Primary Sjögren's syndrome (pSS) is an autoimmune disease in which the underlying cause has yet to be elucidated. The main objective of this study was to determine the T cell receptor (TCR) repertoires of individual… read more here.

Keywords: single cell; cell analysis; cell; th1 th17 ... See more keywords
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Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway.

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recommendations! Published in 2020 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2020.106685

Abstract: Recent studies have reported that the imbalance of T helper 1 cell (Th1), Th17 and regulatory T cell (Treg) have been confirmed to play a vital role in the development of sepsis and other inflammatory… read more here.

Keywords: sepsis; pancreatic injury; baicalin; th1 th17 ... See more keywords
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Fatigue favors in vitro Th1 and Th17-like cell expansion and reduces corticoid sensitivity in MS patients

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recommendations! Published in 2017 at "Journal of Neuroimmunology"

DOI: 10.1016/j.jneuroim.2016.12.013

Abstract: Fatigue is a common "ghost" symptom in patients with multiple sclerosis (MS), an autoimmune disease mediated by T cells that target myelin antigens of the central nervous system. As fatigue has been associated with inflammatory… read more here.

Keywords: patients fatigue; production; fatigue; th1 th17 ... See more keywords
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Physiological low-dose oestrogen promotes the development of experimental autoimmune thyroiditis through the up-regulation of Th1/Th17 responses.

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recommendations! Published in 2018 at "Journal of reproductive immunology"

DOI: 10.1016/j.jri.2018.02.001

Abstract: Previous studies have reported a preponderance of autoimmune thyroiditis (AIT) in females, but the detailed mechanisms have not been elucidated. In this study, we explored the effects of oestrogen on experimental AIT (EAT) and its… read more here.

Keywords: regulation th1; low dose; autoimmune thyroiditis; th1 ... See more keywords
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Addition of a TLR7 agonist to an acellular pertussis vaccine enhances Th1 and Th17 responses and protective immunity in a mouse model.

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recommendations! Published in 2017 at "Vaccine"

DOI: 10.1016/j.vaccine.2017.08.009

Abstract: A resurgence of whooping cough (pertussis) has been observed in recent years in a number of developed countries, despite widespread vaccine coverage. Although the exact reasons of the recurrence of pertussis are not clear, there… read more here.

Keywords: vaccine; acellular pertussis; th1 th17; pertussis ... See more keywords
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Recombinant BCG::Rv2645 elicits enhanced protective immunity compared to BCG in vivo with induced ISGylation-related genes and Th1 and Th17 responses.

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recommendations! Published in 2018 at "Vaccine"

DOI: 10.1016/j.vaccine.2018.04.025

Abstract: There is a need to develop protective vaccines against tuberculosis (TB). Recently, we identified an immunodominant T-cell antigen, Rv2645, from the region of deletion 13 (RD13) of M. tuberculosis (M. tb) H37Rv, which is absent… read more here.

Keywords: enhanced protective; rv2645; th1 th17; related genes ... See more keywords
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Progranulin ameliorates coxsackievirus‐B3‐induced viral myocarditis by downregulating Th1 and Th17 cells

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recommendations! Published in 2018 at "Experimental Cell Research"

DOI: 10.1016/j.yexcr.2018.04.001

Abstract: ABSTRACT Viral myocarditis, which is caused by Coxsackievirus B3 (CVB3) infection, is a leading reason of sudden cardiac death in young adults. Progranulin (PGRN), a pleiotropic growth factor, has been shown to exert anti‐inflammatory function… read more here.

Keywords: viral myocarditis; th17 cells; th1 th17; pgrn ... See more keywords
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MicroRNA-219a-5p suppresses intestinal inflammation through inhibiting Th1/Th17-mediated immune responses in inflammatory bowel disease

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recommendations! Published in 2019 at "Mucosal Immunology"

DOI: 10.1038/s41385-019-0216-7

Abstract: MicroRNA (miR)-219a-5p has been implicated in the development of numerous progression of carcinoma and autoimmune diseases. However, whether miR-219a-5p is involved in the pathogenesis of inflammatory bowel disease (IBD) remains elusive. In this study, we… read more here.

Keywords: mir 219a; th1 th17; inflammation; cd4 cells ... See more keywords