Th17 cells and their cytokines serve as potential therapeutic target in experimental autoimmune neuritis
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1478
Abstract: Accumulating evidence has pointed that T helper 17 cells and their cytokines are pathogenic in Guillain–Barré syndrome (GBS). However, little is known concerning the IL‐17 expression change trend during the whole course of disease, and… read more here.
Keywords: experimental autoimmune; cells cytokines; th17 cells; autoimmune neuritis ... See more keywords
Effects of Th17 cells and IL‐17 in the progression of cervical carcinogenesis with high‐risk human papillomavirus infection
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1279
Abstract: The existence of Th17 cells and IL‐17 was recently shown in several types of infectious diseases, but their distribution and functions in cervical lesions with high‐risk human papillomavirus (HPV) infection have not been fully elucidated.… read more here.
Keywords: high risk; infection; th17 cells; risk human ... See more keywords
Musculin inhibits human T‐helper 17 cell response to interleukin 2 by controlling STAT5B activity
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201746996
Abstract: We recently demonstrated that human T‐helper (Th) 17 cells, unlike Th1 cells, do not proliferate in response to T‐cell receptor stimulation, mainly because of their reduced capacity to produce and respond to IL‐2. In this… read more here.
Keywords: response; human helper; th17 cells; th17 ... See more keywords
Point mutation L116R in interferon‐regulatory factor 4 differentially impacts key cytokine production in Th2, Th9, and Th17 cells
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202249869
Abstract: Upon first activation, CD4+ T cells differentiate into specialized T helper subtypes, dependent on the key transcription factors (TFs) T-bet for Th1, GATA3 for Th2, PU.1 for Th9, and RORγt for Th17. Our group established… read more here.
Keywords: irf4; th17 cells; th9; production ... See more keywords
From NAFLD to HCC: Is IL‐17 the crucial link?
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28934
Abstract: Nonalcoholic fatty liver disease (NAFLD) has an increasing prevalence worldwide and is relevant for liver-related as well as overall morbidity and mortality. Patients with active inflammatory NAFLD, termed nonalcoholic steatohepatitis (NASH), are at particular risk… read more here.
Keywords: hcc; inflammation; th17 cells; mice ... See more keywords
Circulating JNK pathway‐associated phosphatase: A novel biomarker correlates with Th17 cells, acute exacerbation risk, and severity in chronic obstructive pulmonary disease patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24153
Abstract: JNK pathway‐associated phosphatase (JKAP) involves in the regulation of inflammation, immunity, and lung injury. The current study aimed to investigate correlation of JKAP with Th1, Th17 cells, acute exacerbation risk, and disease severity in chronic… read more here.
Keywords: jnk pathway; th17 cells; cells acute; associated phosphatase ... See more keywords
Th1, Th2, and Th17 cells are dysregulated, but only Th17 cells relate to C‐reactive protein, D‐dimer, and mortality risk in Stanford type A aortic dissection patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24469
Abstract: T helper (Th) cells are closely involved in vascular inflammation, endothelial dysfunction, and atherogenesis, which are the hallmarks of aortic dissection (AD). This study aimed to evaluate the clinical value of Th1, Th2, and Th17… read more here.
Keywords: th17 cells; aortic dissection; th2 th17; th1 th2 ... See more keywords
Blood Th17 cells and IL‐17A as candidate biomarkers estimating the progression of cognitive impairment in stroke patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24581
Abstract: T helper (Th) cells regulate immunity and inflammation to engage in cognitive impairment in several neurological diseases, while their clinical relevance in stroke patients is not clear. The current study intended to assess the relationship… read more here.
Keywords: th17 cells; blood th17; cognitive impairment; cells 17a ... See more keywords
Regulatory T and T helper 17 cells: Their roles in preeclampsia
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DOI: 10.1002/jcp.26604
Abstract: Regulatory T (Treg) cells have been identified as key immune regulators and are important to fetal survival within the maternal uterus. T helper 17 (Th17) cells have also emerged as a new subset of effector… read more here.
Keywords: treg cells; regulatory helper; th17 cells; helper cells ... See more keywords
Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-017-1965-3
Abstract: Adoptive cellular therapy (ACT) with the Th17 subset of CD4+ T cells can cure established melanoma in preclinical models and holds promise for treating human cancer. However, little is known about the growth factors necessary… read more here.
Keywords: th17 cells; receptor gamma; depletion; th17 ... See more keywords
Anti-Dll4 Antibody Inhibits the Differentiation of Th17 Cells in Asthmatic Mice
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0638-x
Abstract: T helper 17 (Th17) cells play an important role in allergic asthma, and the Notch ligand Delta-like ligand (Dll)4 has been reported to direct the differentiation of Th17 cells. In this study, experimental animals were… read more here.
Keywords: dll4 antibody; group; anti dll4; th17 cells ... See more keywords