Human dendritic cells activated with MV130 induce Th1, Th17 and IL‐10 responses via RIPK2 and MyD88 signalling pathways
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747024
Abstract: Recurrent respiratory tract infections (RRTIs) are the first leading cause of community‐ and nosocomial‐acquired infections. Antibiotics remain the mainstay of treatment, enhancing the potential to develop antibiotic resistances. Therefore, the development of new alternative approaches… read more here.
Keywords: signalling pathways; responses via; dendritic cells; th1 th17 ... See more keywords
Physiological low-dose oestrogen promotes the development of experimental autoimmune thyroiditis through the up-regulation of Th1/Th17 responses.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2018.02.001
Abstract: Previous studies have reported a preponderance of autoimmune thyroiditis (AIT) in females, but the detailed mechanisms have not been elucidated. In this study, we explored the effects of oestrogen on experimental AIT (EAT) and its… read more here.
Keywords: regulation th1; low dose; autoimmune thyroiditis; th1 ... See more keywords
Addition of a TLR7 agonist to an acellular pertussis vaccine enhances Th1 and Th17 responses and protective immunity in a mouse model.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.08.009
Abstract: A resurgence of whooping cough (pertussis) has been observed in recent years in a number of developed countries, despite widespread vaccine coverage. Although the exact reasons of the recurrence of pertussis are not clear, there… read more here.
Keywords: vaccine; acellular pertussis; th1 th17; pertussis ... See more keywords
Elevated IL‐23 in skin promotes IL‐23 derived Th17 responses in leprosy patients
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13689
Abstract: Leprosy is an infectious disease caused by non‐cultivable bacteria Mycobacterium leprae. Th17 cells play vital roles during pathogenesis of leprosy reactions and IL‐23 is involved in Th17 cell differentiation. Although previous studies have reported the… read more here.
Keywords: skin promotes; elevated skin; promotes derived; derived th17 ... See more keywords
The Role of Flavonoids in Inhibiting Th17 Responses in Inflammatory Arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Immunology Research"
DOI: 10.1155/2018/9324357
Abstract: Flavonoids have been considered powerful anti-inflammatory agents, and their exact immunomodulatory action as therapeutic agents in autoimmune diseases has started to emerge. Their role in the manipulation of immunoregulation is less understood. Several studies attempted… read more here.
Keywords: role flavonoids; flavonoids inhibiting; autoimmune diseases; role ... See more keywords