Functionally distinct IFN‐γ+IL‐17A+ Th cells in experimental autoimmune uveitis: T‐cell heterogeneity, migration, and steroid response
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DOI: 10.1002/eji.202048616
Abstract: Immunopathogenic roles for both Th1 (CD4+IFN‐γ+) and Th17 (CD4+IL‐17A+) cells have been demonstrated in experimental autoimmune uveitis (EAU). However, the role for Th17/Th1 (CD4+ T cells co‐expressing IFN‐γ and IL‐17A) cells in EAU is not… read more here.
Keywords: th17 th1; th1 cells; th1; migration ... See more keywords
Malt1 inactivation attenuates experimental colitis through the regulation of Th17 and Th1/17 cells
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DOI: 10.1007/s00011-018-1207-y
Abstract: Objective and designProtease activity of MALT lymphoma-translocation protein 1 (Malt1) plays an important role in the development of colitis, but the detailed mechanism has not been fully elucidated.MethodEffects of Malt1 protease on the activation of… read more here.
Keywords: th17 th1; th1 cells; malt1; colitis ... See more keywords
TFAP2C exacerbates psoriasis-like inflammation by promoting Th17 and Th1 cells activation through regulating TEAD4 transcription
Sign Up to like & getrecommendations! Published in 2023 at "Allergologia et Immunopathologia"
DOI: 10.15586/aei.v51i3.854
Abstract: Background: Psoriasis is one of the chronic and autoimmune skin diseases. It is important to uncover the mechanisms underlying the psoriasis. Transcription factor activator protein (TFAP-2) gamma, also known as AP2-gamma, is a protein encoded… read more here.
Keywords: th17 th1; transcription; th1 cells; tfap2c ... See more keywords