Plasmacytoid dendritic cells suppress Th2 responses induced by epicutaneous sensitization
Sign Up to like & getrecommendations! Published in 2020 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12315
Abstract: Epicutaneous (EC) sensitization with protein allergens is the most important sensitization route for atopic dermatitis. Plasmacytoid dendritic cells (pDCs) are characterized by massive secretion of interferon‐α (IFNα). B6 mice are T helper type 1 (Th1)‐prone… read more here.
Keywords: th2 responses; dendritic cells; epicutaneous sensitization; balb mice ... See more keywords
IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006173
Abstract: Respiratory paramyxoviruses are important causes of morbidity and mortality, particularly of infants and the elderly. In humans, a T helper (Th)2-biased immune response to these infections is associated with increased disease severity; however, little is… read more here.
Keywords: th2 responses; infection; immunopathology; parainfluenza virus ... See more keywords
B Cell IL-4 Drives Th2 Responses In Vivo, Ameliorates Allograft Rejection, and Promotes Allergic Airway Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.762390
Abstract: B cells can be polarized to express various cytokines. The roles of IFNγ and IL-10, expressed respectively by B effector 1 (Be1) and Bregs, have been established in pathogen clearance, tumor growth, autoimmunity and allograft… read more here.
Keywords: cell; allograft rejection; allergic airway; th2 responses ... See more keywords