IL2-inducible T-cell kinase inhibitor ibrutinib reduces symptoms and Th2 differentiation in mouse allergic-rhinitis model.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21884
Abstract: Th2 and Th17 immune response contribute to allergic rhinitis (AR) development. Targeting Th2 and Th17 response has been shown to ameliorate AR. Ibrutinib is an inhibitor for IL2-inducible T-cell kinase, which can promote Th2 and… read more here.
Keywords: allergic rhinitis; ibrutinib; model; th2 th17 ... See more keywords
Th1, Th2, and Th17 cells are dysregulated, but only Th17 cells relate to C‐reactive protein, D‐dimer, and mortality risk in Stanford type A aortic dissection patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24469
Abstract: T helper (Th) cells are closely involved in vascular inflammation, endothelial dysfunction, and atherogenesis, which are the hallmarks of aortic dissection (AD). This study aimed to evaluate the clinical value of Th1, Th2, and Th17… read more here.
Keywords: th17 cells; aortic dissection; th2 th17; th1 th2 ... See more keywords
Simultaneous analysis of multiple T helper subsets in leprosy reveals distinct patterns of Th1, Th2, Th17 and Tregs markers expression in clinical forms and reactional events
Sign Up to like & getrecommendations! Published in 2017 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-017-0519-9
Abstract: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Previous studies have demonstrated that the difference among clinical forms of leprosy can be associated with the immune response of patients, mainly by T helper… read more here.
Keywords: clinical forms; reactional events; th17 tregs; th2 th17 ... See more keywords
Role of the IL-23-T-bet/GATA3 Axis for the Pathogenesis of Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01358-y
Abstract: Ulcerative colitis (UC) has been considered a Th2- and Th17-related disease. However, anti-IL-12/23 p40 antibody, which blocks Th1 and Th17 cell induction and maintenance, has shown efficacy in treating UC, suggesting that UC might not… read more here.
Keywords: th2 th17; expression; ulcerative colitis; bet gata3 ... See more keywords
Piper nigrum extract ameliorated allergic inflammation through inhibiting Th2/Th17 responses and mast cells activation.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.10.005
Abstract: Piper nigrum (Piperaceae) is commonly used as a spice and traditional medicine in many countries. P. nigrum has been reported to have anti-oxidant, anti-bacterial, anti-tumor, anti-mutagenic, anti-diabetic, and anti-inflammatory properties. However, the effect of P.… read more here.
Keywords: piper nigrum; mast cells; anti ova; anti ... See more keywords
Interleukin‐16 aggravates ovalbumin‐induced allergic inflammation by enhancing Th2 and Th17 cytokine production in a mouse model
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1111/imm.13068
Abstract: Asthma is a chronic inflammatory disease that involves a variety of cytokines and cells. Interleukin‐16 (IL‐16) is highly expressed during allergic airway inflammation and is involved in its development. However, its specific mechanism of action… read more here.
Keywords: cytokine; inflammation; th17 cytokine; induced allergic ... See more keywords
Th1/Th2/Th17 cytokine profile in hepatic cystic Echinococcosis patients with different cyst stages
Sign Up to like & getrecommendations! Published in 2021 at "Parasite Immunology"
DOI: 10.1111/pim.12839
Abstract: The study aimed to investigate possible correlation between expression level of Th1/Th2/Th17‐type profile and cyst viability in the systemic and local immunity of hepatic cystic Echinococcosis (CE) patients. read more here.
Keywords: cystic echinococcosis; echinococcosis patients; hepatic cystic; th2 th17 ... See more keywords
Circulating Th1, Th2, and Th17 Levels in Hypertensive Patients
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DOI: 10.1155/2017/7146290
Abstract: Background Evidence from experimental studies showed that Th1, Th2, and Th17 play a pivotal role in hypertension and target organ damage. However, whether changes in the circulating Th1, Th2, and Th17 levels are associated with… read more here.
Keywords: hypertensive patients; th2 th17; th17 levels; th1 th2 ... See more keywords
Outer Membrane Vesicles Coating Nano-Glycyrrhizic Acid Confers Protection Against Borderella bronchiseptica Through Th1/Th2/Th17 Responses
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s350846
Abstract: Purpose Outer membrane vesicles (OMVs) are spherical nano-sized proteolipids secreted by numerous pathogenic Gram-negative bacteria. Due to the immunostimulatory properties and protective efficacy, OMVs have received increasing attention as a candidate for the vaccine to… read more here.
Keywords: outer membrane; membrane vesicles; th1 th2; gan omv ... See more keywords
Expression and Clinical Significance of Th1/Th2/Th17 Cytokines and Lymphocyte Subsets in PCNSL
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s366761
Abstract: Purpose Primary central nervous system lymphoma (PCNSL) responds favorably to radiation, chemotherapy and targeted drug therapy. However survival is usually worse, the treatment-related drug resistance and recurrence are still clinical problems to be solved urgently.… read more here.
Keywords: lymphocyte subsets; th2 th17; th1 th2; treatment ... See more keywords
255-LB: The Role of Th1, Th2, Th17, and Treg Cells in Various Clinical Phases of Type 1 Diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.2337/db19-255-lb
Abstract: Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycaemia due to insulin production/secretion disorder or insulin resistance caused by various pathogenetic mechanisms. T helper cells (Th) play an important role in the pathogenesis of… read more here.
Keywords: role; none; treg; th1 th2 ... See more keywords