Point mutation L116R in interferon‐regulatory factor 4 differentially impacts key cytokine production in Th2, Th9, and Th17 cells
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DOI: 10.1002/eji.202249869
Abstract: Upon first activation, CD4+ T cells differentiate into specialized T helper subtypes, dependent on the key transcription factors (TFs) T-bet for Th1, GATA3 for Th2, PU.1 for Th9, and RORγt for Th17. Our group established… read more here.
Keywords: irf4; th17 cells; th9; production ... See more keywords