Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals
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DOI: 10.1038/s41385-020-0286-6
Abstract: Gut CD4 + T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequencies.… read more here.
Keywords: infected individuals; ccl20; th17 cells; th22 cells ... See more keywords
Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/8071234
Abstract: The interaction of immune cells and cytokines in the tumor microenvironment affects the development and prognosis of tumors with an unclear potential regulatory mechanism. Recent studies have elucidated the protumor role of Th22 cells and… read more here.
Keywords: lung cancer; cell; th22 cells;
Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis
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DOI: 10.3389/fimmu.2018.02901
Abstract: T helper (Th) cells can differentiate into functionally distinct subsets and play a pivotal role in inflammatory and autoimmune diseases such as rheumatoid arthritis (RA). Th22 cells have been identified as a new subset secreting… read more here.
Keywords: osteoclast differentiation; production; th22 cells; th22 ... See more keywords
The Role of T Helper 22 Cells in Dermatological Disorders
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DOI: 10.3389/fimmu.2022.911546
Abstract: T helper 22 (Th22) cells are a newly identified subset of CD4+ T cells that secrete the effector cytokine interleukin 22 (IL-22) upon specific antigen stimulation, barely with IFN-γ or IL-17. Increasing studies have demonstrated… read more here.
Keywords: role helper; cells dermatological; helper; helper cells ... See more keywords
Role of Th22 Cells in Human Viral Diseases
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DOI: 10.3389/fmed.2021.708140
Abstract: Naive CD4+ T cells can differentiate into different cell subsets after receiving antigen stimulation, which secrete corresponding characteristic cytokines and thereby exert biological effects in various diseases. Th22 cells, a novel subset of CD4+ T… read more here.
Keywords: human viral; th22 cells; th22; cells human ... See more keywords
Current Knowledge of Th22 Cell and IL-22 Functions in Infectious Diseases
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DOI: 10.3390/pathogens12020176
Abstract: T helper 22 (Th22) cells, a newly defined CD4+ T-cell lineage, are characterized by their distinct cytokine profile, which primarily consists of IL-13, IL-22 and TNF-α. Th22 cells express a wide spectrum of chemokine receptors,… read more here.
Keywords: current knowledge; cell; infectious diseases; knowledge th22 ... See more keywords