Decreased frequency of circulating Th9 cells in patients with chronic hepatitis B infection
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22246
Abstract: Chronic hepatitis B (CHB) is one of the major infectious diseases in which CD4+ T helper (Th) cells play a crucial role. Th9 cells are a distinct subset of CD4+ Th cells with important physiological… read more here.
Keywords: decreased frequency; circulating th9; th9 cells; chronic hepatitis ... See more keywords
Flow Cytometric Assessment of STAT Molecules in Th9 Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6877-0_10
Abstract: IL-9-producing Th9 cells are a novel subset of T helper cells that develop independently of other T helper subsets. Th9 cells have been implicated in the pathogenesis of allergic asthma and autoimmunity, while also serving… read more here.
Keywords: th9 cells; flow cytometric; assessment stat; cytometric assessment ... See more keywords
Isolation and Purification of Th9 Cells for the Study of Inflammatory Diseases in Research and Clinical Settings.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6877-0_19
Abstract: Th9 cells are associated with atopic and inflammatory diseases, and their increased levels and function correlate with the severity of symptoms in various inflammatory disorders including asthma, food allergy, atopic dermatitis, ulcerative colitis, and psoriatic… read more here.
Keywords: purification th9; th9 cells; isolation purification; inflammatory diseases ... See more keywords
A Method to In Vitro Differentiate Th9 Cells from Mouse Naïve CD4+ T Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6877-0_4
Abstract: CD4+ T helper cells with the ability to produce effector cytokines provide host protection by regulating immune responses against pathogens. In contrast, these cells are responsible for the development of various inflammatory disease if not… read more here.
Keywords: cd4 cells; th9 cells; differentiate; th9 ... See more keywords
Prediction and Validation of Transcription Factors Binding Sites in the Il9 Locus.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6877-0_9
Abstract: Over the past decade, multiple effector T cell subsets have been identified with varying differentiation conditions in the milieu as well as a broad diversity of cytokine expression. Interleukin-9 (IL-9) secreting T helper 9 (Th9)… read more here.
Keywords: transcription; prediction validation; validation transcription; th9 cells ... See more keywords
Adoptive transfer of tumor-specific Th9 cells eradicates heterogeneous antigen-expressing tumor cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer cell"
DOI: 10.1016/j.ccell.2021.10.013
Abstract: In this issue of Cancer Cell, Xue et al. demonstrate that adoptive transfer of tumor-specific Th9 cells can eradicate established tumors containing antigen-loss-variant cells (ALVs) through both direct killing and bystander effects mediated by intratumoral accumulation… read more here.
Keywords: th9 cells; tumor specific; adoptive transfer; transfer tumor ... See more keywords
Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials.
Sign Up to like & getrecommendations! Published in 2017 at "Human immunology"
DOI: 10.1016/j.humimm.2016.12.010
Abstract: Naïve CD4+ T cells are pleiotropically divided into various T helper (Th) cell subsets, according to their pivotal roles in the regulation of immune responses. The differentiation of Th9 cells, an interleukin (IL)-9 producing subset,… read more here.
Keywords: disorders pathogenesis; th9 cells; autoimmune disorders; therapeutic potentials ... See more keywords
Harnessing TH9 cells in cancer immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in immunology"
DOI: 10.1016/j.smim.2021.101477
Abstract: CD4 T cell effector subsets not only profoundly affect cancer progression, but recent evidence also underscores their critical contribution to the anticancer efficacy of immune checkpoint inhibitors. In 2012, the two seminal studies suggested the… read more here.
Keywords: th9 cells; cells cancer; cancer immunotherapy; cancer ... See more keywords
What’s old is new again: Batf transcription factors and Th9 cells
Sign Up to like & getrecommendations! Published in 2019 at "Mucosal Immunology"
DOI: 10.1038/s41385-019-0155-3
Abstract: Hubble’s law, established by famed astronomer Edwin Hubble, states that the universe is rapidly expanding. Although more figuratively, the same can be said of the rapidly expanding universe of CD4 T cells. In 1986, Mosmann… read more here.
Keywords: transcription; th9 cells; th9; mucosal ... See more keywords
Fatty acid metabolism constrains Th9 cell differentiation and antitumor immunity via the modulation of retinoic acid receptor signaling
Sign Up to like & getrecommendations! Published in 2024 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-024-01209-y
Abstract: T helper 9 (Th9) cells are interleukin 9 (IL-9)-producing cells that have diverse functions ranging from antitumor immune responses to allergic inflammation. Th9 cells differentiate from naïve CD4+ T cells in the presence of IL-4… read more here.
Keywords: differentiation; cell differentiation; th9 cell; th9 cells ... See more keywords
The emerging role of T helper 9 (Th9) cells in immunopathophysiology: A comprehensive review of their effects and responsiveness in various disease states
Sign Up to like & getrecommendations! Published in 2024 at "International Reviews of Immunology"
DOI: 10.1080/08830185.2024.2364586
Abstract: Abstract Th9 cells, a subset of T-helper cells producing interleukin-9 (IL-9), play a vital role in the adaptive immune response and have diverse effects in different diseases. Regulated by transcription factors like PU.1 and IRF4,… read more here.
Keywords: cancer; disease; role; review ... See more keywords