Subtotal and total splenectomy for hereditary pyropoikilocytosis: Benefits and outcomes
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25223
Abstract: single-agent chelation therapies. Br J Haematol. 2011;15(5):654-656. 4. Elalfy M, Adly AM, Wali Y, Tony S, Samir A, Elhenawy YI. Efficacy and safety of a novel combination of two oral chelators deferasirox/deferiprone over deferoxamine/deferiprone in… read more here.
Keywords: major patients; total splenectomy; hereditary pyropoikilocytosis; thalassemia major ... See more keywords
Overall and complication‐free survival in a large cohort of patients with β‐thalassemia major followed over 50 years
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26798
Abstract: We report data on survival and complications for a longitudinal cohort of 709 transfusion‐dependent β‐thalassemia major patients (51.1% males) born between 1970 and 1997 and followed through 2020 at seven major centers in Italy. Overall… read more here.
Keywords: thalassemia major; disease; complication; survival ... See more keywords
Detection of HCV genome in peripheral blood mononuclear cells of Iranian seropositive and HCV RNA negative in plasma of patients with beta‐thalassemia major: Occult HCV infection
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25279
Abstract: Beta (β) thalassemia major is a genetic blood disorder with a deficiency in the hemoglobin beta chain, requiring blood transfusion therapy. Multiple blood transfusions increase the risk of transmitting blood‐borne infections. The aim of this… read more here.
Keywords: hcv; thalassemia major; hcv rna; hcv infection ... See more keywords
Increased levels of advanced glycation end products positively correlate with iron overload and oxidative stress markers in patients with β-thalassemia major
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Hematology"
DOI: 10.1007/s00277-017-3223-3
Abstract: The impaired biosynthesis of the β-globin chain in β-thalassemia leads to the accumulation of unpaired alpha globin chains, failure in hemoglobin formation, and iron overload due to frequent blood transfusion. Iron excess causes oxidative stress… read more here.
Keywords: oxidative stress; iron; thalassemia major; iron overload ... See more keywords
Novel retinal findings in β-thalassemia major: older age and higher ferritin level as the risk factors
Sign Up to like & getrecommendations! Published in 2021 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-021-05141-z
Abstract: To investigate retinal changes in β-thalassemia major patients and identify their association with systemic risk factors. In this prospective study, 120 β-thalassemia major patients received complete ophthalmic examinations (best-corrected visual acuity, contrast sensitivity, color vision,… read more here.
Keywords: related retinal; thalassemia major; risk factors; level ... See more keywords
Socio-religious Prognosticators of Psychosocial Burden of Beta Thalassemia Major
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Religion and Health"
DOI: 10.1007/s10943-020-01069-6
Abstract: The study investigates the socio-religious factors in the propagation of genetically inherited disease of Beta thalassemia. The disorder which reportedly has a significant protraction through repeated cousin marriages results in the social maladjustment of the… read more here.
Keywords: burden beta; socio religious; thalassemia major; beta ... See more keywords
Mirror aneurysms of extracranial internal carotid arteries in a patient with beta-thalassemia major
Sign Up to like & getrecommendations! Published in 2020 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-020-01379-2
Abstract: Beta-thalassemia major is a chronic disorder characterised by severe anemia. This patient with beta-thalassemia major is the first magnetic resonance (MR) angiographic case for symmetric mirror aneurysms of the extracranial internal carotid arteries. For diagnosis… read more here.
Keywords: beta thalassemia; patient beta; mirror aneurysms; thalassemia major ... See more keywords
"DXA and pQCT derived parameters in Indian children with Beta thalassemia major- a case controlled study".
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115730
Abstract: Children with beta thalassemia major (BTM) are known to have reduced bone mass which increases incidence of non-traumatic fractures. Few studies have assessed prevalence of fractures and bone health in underprivileged children with BTM. Our… read more here.
Keywords: children beta; children btm; thalassemia major; bone ... See more keywords
The impact of silymarin on antioxidant and oxidative status in patients with β-thalassemia major: A crossover, randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2017 at "Complementary therapies in medicine"
DOI: 10.1016/j.ctim.2017.08.007
Abstract: BACKGROUND & AIMS Blood transfusion therapy is lifesaving for individuals with β-thalassemia major (β-TM). Iron burden following blood transfusion is the main cause of oxidative stress (OS) and organ dysfunction in these patients. The aim… read more here.
Keywords: oxidative status; silymarin; thalassemia major; antioxidant oxidative ... See more keywords
Asymptomatic actinomycosis in a girl with thalassemia major
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DOI: 10.1016/j.idcr.2019.e00602
Abstract: We present a rare case of lung actinomycosis in a girl with thalassemia major with a competent immunological status. Chest computed tomography scans showed high intensity nodules in the right lower lung. Diagnosis was confirmed… read more here.
Keywords: girl thalassemia; actinomycosis girl; thalassemia major;
Can biomarkers predict myocardial iron overload in children with thalassemia major?
Sign Up to like & getrecommendations! Published in 2023 at "Cardiology in the young"
DOI: 10.1017/s1047951122004206
Abstract: AIM Beta-thalassemia major requires regular blood transfusions throughout life, which in turn leads to iron accumulation in the body. While cardiac T2* MRI is the gold standard in determining cardiac iron accumulation, it is not… read more here.
Keywords: thalassemia major; iron; differentiation factor; iron accumulation ... See more keywords