Detection of Δ9 THC in oral fluid following vaporized cannabis with varied cannabidiol (CBD) content: An evaluation of two point‐of‐collection testing devices
Sign Up to like & getrecommendations! Published in 2019 at "Drug Testing and Analysis"
DOI: 10.1002/dta.2687
Abstract: Abstract Point‐of‐collection testing (POCT) for Δ9‐tetrahydrocannabinol (THC) in oral fluid is increasingly used to detect driving under the influence of cannabis (DUIC). However, previous studies have questioned the reliability and accuracy of two commonly used… read more here.
Keywords: oral fluid; cbd; point collection; thc cbd ... See more keywords
THC/CBD oromucosal spray in patients with multiple sclerosis overactive bladder: a pilot prospective study
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Sciences"
DOI: 10.1007/s10072-017-3148-6
Abstract: Lower urinary tract dysfunctions (LUTDs) are commonly reported in multiple sclerosis (MS) patients and are mainly related to neurogenic overactive bladder (OAB). The aim of this observational study was to assess the effect of a… read more here.
Keywords: overactive bladder; cbd oromucosal; bladder; thc cbd ... See more keywords
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.09.007
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Glioblastoma multiforme (GBM) is the most frequent and aggressive type of brain tumor due, at least in part, to its poor response to current anticancer treatments. These features… read more here.
Keywords: cbd; initiating cells; glioma initiating; tmz ... See more keywords
The effect of delta-9-tetrahydrocannabinol and cannabidiol on p50 of the oxygen haemoglobin dissociation curve.
Sign Up to like & getrecommendations! Published in 2020 at "Fitoterapia"
DOI: 10.1016/j.fitote.2020.104539
Abstract: Cannabis is one of the most chemically complex plants containing a large number of compounds, among which are cannabinoids; the main biologically active constituents of the plant. Delta-9-tetrahydrocannabinol (THC) is known as the main psychoactive… read more here.
Keywords: oxygen; delta tetrahydrocannabinol; p50 oxygen; thc cbd ... See more keywords
THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
Sign Up to like & getrecommendations! Published in 2017 at "Forensic science international"
DOI: 10.1016/j.forsciint.2017.04.006
Abstract: BACKGROUND AND AIMS Several publications have suggested increasing cannabis potency over the last decade, which, together with lower amounts of cannabidiol (CBD), could contribute to an increase in adverse effects after cannabis smoking. Naturalistic studies… read more here.
Keywords: cbd blood; blood samples; thc cbd; cbd ... See more keywords
PTL401, a New Formulation Based on Pro-Nano Dispersion Technology, Improves Oral Cannabinoids Bioavailability in Healthy Volunteers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.12.020
Abstract: There is a growing clinical interest in developing and commercializing pharmaceutical-grade cannabinoid products, containing primarily tetrahydrocannabinol (THC) and cannabidiol (CBD). The oral bioavailability of THC and CBD is very low due to extensive "first-pass" metabolism.… read more here.
Keywords: cbd; bioavailability; thc cbd; thc ... See more keywords
Rapid In Situ Detection of THC and CBD in Cannabis sativa L. by 1064 nm Raman Spectroscopy
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c01629
Abstract: The need to find a rapid and worthwhile technique for the in situ detection of the content of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in Cannabis sativa L. is an ever-increasing problem in the forensic field.… read more here.
Keywords: spectroscopy; thc cbd; thc; raman spectroscopy ... See more keywords
Effects of oral Δ9-tetrahydrocannabinol and cannabidiol combinations on a sustained attention task in rats.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental and clinical psychopharmacology"
DOI: 10.1037/pha0000635.supp
Abstract: A well-documented side effect of cannabis and Δ9-tetrahydrocannabinol (THC) acute administration is deficits in cognition and attention. Cannabidiol (CBD), a nonintoxicating constituent of cannabis, may modulate THC's impairing effects. A goal of this study was… read more here.
Keywords: tetrahydrocannabinol; sustained attention; cannabidiol; thc cbd ... See more keywords
Activity of THC, CBD, and CBN on Human ACE2 and SARS-CoV1/2 Main Protease to Understand Antiviral Defense Mechanism.
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DOI: 10.1055/a-1581-3707
Abstract: THC, CBD, and CBN were reported as promising candidates against SARS-CoV2 infection, but the mechanism of action of these three cannabinoids is not understood. This study aims to determine the mechanism of action of THC,… read more here.
Keywords: mechanism; cbd; cbd cbn; main protease ... See more keywords
Absorbance-Transmittance Excitation Emission Matrix Method for Quantification of Major Cannabinoids and Corresponding Acids: A Rapid Alternative to Chromatography for Rapid Chemotype Discrimination of Cannabis sativa Varieties.
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DOI: 10.1089/can.2021.0165
Abstract: Background: Phytocannabinoids naturally occur in the cannabis plant (Cannabis sativa), and Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) predominate. There is a need for rapid inexpensive methods to quantify total THC (for statutory definition) and THC-CBD ratio… read more here.
Keywords: total thc; cannabis; hplc; thc cbd ... See more keywords
Δ9-THC and CBD in Plasma, Oral Fluid, Exhaled Breath, and Urine from 23 Patients Administered Sativex.
Sign Up to like & getrecommendations! Published in 2023 at "Cannabis and cannabinoid research"
DOI: 10.1089/can.2022.0179
Abstract: Background: Detecting the presence of Δ9-THC and CBD is mainly done through venous blood sampling, but other methods are becoming available. Oromucosal administration of Δ9-THC and CBD is less studied than inhalation, but this mode… read more here.
Keywords: oral fluid; exhaled breath; thc cbd;