Quantification of Cannabinoids in Human Hair using A modified Derivatisation Procedure and Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3005
Abstract: The aim of this work was to develop and validate a liquid chromatography tandem mass spectrometry method for detecting of the main cannabinoids, of cannabinol (CBN) and tetrahydrocannabinol (THC) and the primary metabolite 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH)… read more here.
Keywords: chromatography tandem; hair; thc cooh; liquid chromatography ... See more keywords
A laboratory-study on the analytical determination and removal processes of THC-COOH and bezoylecgonine in the activated sludge reactor.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.01.117
Abstract: The present study focused on 11-nor-9carboxy-Δ9-THC (THC-COOH) and Benzoylecgonine (BE), the most common metabolites of cannabis and cocaine, respectively, present in the domestic sewage entering the wastewater treatment plants. The aims of the study were:… read more here.
Keywords: removal; study; thc cooh; activated sludge ... See more keywords
Validation of Serum Tetrahydrocannabinol Assay and Its Clinical Application
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqae129.392
Abstract: The widespread use of marijuana across all age groups in the United States, driven by the legalization of recreational and medical cannabis, has underscored the need for accurate measurement of tetrahydrocannabinol (THC) and its metabolites… read more here.
Keywords: thc metabolites; thc; serum tetrahydrocannabinol; validation serum ... See more keywords
The Cannabinoids Tetrahydrocannabinol, Cannabinol, Cannabidiol, Tetrahydrocannabivarin, and 11-nor-9-carboxy-∆9-THC in Hair.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkab068
Abstract: The cannabinoids tetrahydrocannabinol (THC), tetrahydrocannabivarin (THCV), cannabidiol (CBD), cannabinol (CBN) and (-)-11-nor-9-carboxy-∆9-tetrahydrocannabinol (THC-COOH) were determined in 4773 hair samples. Confirmation of THC-COOH was by GC-MS/MS. Confirmation of THC, THCV, CBN and CBD was by LC-MS/MS… read more here.
Keywords: hair; cannabinoids tetrahydrocannabinol; thc cooh; cannabidiol ... See more keywords
Prevalence of Cannabidiol, Δ9- and Δ8-Tetrahydrocannabinol and Metabolites in Workplace Drug Testing Urine Specimens.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac013
Abstract: Given the recent popularity of cannabidiol (CBD) use and the emergence of Δ8-tetrahydrocannabinol (Δ8-THC), the prevalence and concentration of these and other cannabinoids was investigated in 2,000 regulated and 4,000 non-regulated specimens from workplace drug… read more here.
Keywords: cbd; workplace drug; cannabidiol; thc cooh ... See more keywords
Urinary Excretion Profile of Cannabinoid Analytes Following Acute Administration of Oral and Vaporized Cannabis in Infrequent Cannabis Users.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac042
Abstract: Traditionally, smoking has been the predominant method for administering cannabis, but alternative routes of administration have become more prevalent. Additionally, research examining urinary cannabinoid excretion profiles has primarily focused on 11-nor-9-carboxy-∆9-tetrahydrocannabinol (Δ9-THC-COOH), a metabolite of… read more here.
Keywords: administration; cannabis; oral vaporized; thc cooh ... See more keywords
Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts Varies as a Function of Screening Criterion Used
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000001032
Abstract: ABSTRACT The authors recruited nineteen daily users of retail oral hemp-derived CBD products (≤0.3% Δ9-tetrahydrocannbinol; THC) and collected urine samples that were screened for 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH), a metabolite of THC. Urine samples were aliquoted into… read more here.
Keywords: hemp; daily use; criterion; thc cooh ... See more keywords
Interpretation of Cannabis Findings in the Hair of Very Young Children: Mission Impossible.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201019666171129180206
Abstract: BACKGROUND Hair has been suggested since the middle of the 90's to be a suitable matrix to document repetitive exposure to cannabis. Because it is possible to detect Δ9-tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD)… read more here.
Keywords: cannabis; interpretation; hair; thc cooh ... See more keywords
Is the Urine Cannabinoid Level Measured via a Commercial Point-of-Care Semiquantitative Immunoassay a Cannabis Withdrawal Syndrome Severity Predictor?
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2020.598150
Abstract: Background: For cannabis-dependent subjects, the relationship between cannabis withdrawal syndrome (CWS) severity and the urine cannabinoid concentrations are unclear; we investigated this using a commercial point-of-care (POC) enzyme immunoassay detecting 11-nor-9-carboxy-Delta-9-tetrahydrocannabinol (THC-COOH). Methods: Observational study… read more here.
Keywords: cannabis withdrawal; thc cooh; severity;
Metabolites of Cannabis Induce Cardiac Toxicity and Morphological Alterations in Cardiac Myocytes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031401
Abstract: Cannabis is one of the most commonly used recreational drugs worldwide. Rrecent epidemiology studies have linked increased cardiac complications to cannabis use. However, this literature is predominantly based on case incidents and post-mortem investigations. This… read more here.
Keywords: cell; metabolites cannabis; thc thc; thc cooh ... See more keywords
Are Δ9-Tetrahydrocannabinol and Its Major Metabolites Substrates or Inhibitors of Placental or Human Hepatic Drug Solute-Carrier Transporters?
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252212036
Abstract: Δ9-Tetrahydrocannabinol (THC) is the primary psychoactive component of cannabis which is being increasingly consumed by pregnant people. In humans, THC is sequentially metabolized in the liver to its circulating metabolites 11-hydroxy-THC (11-OH-THC, psychoactive) and 11-nor-9-carboxy-THC… read more here.
Keywords: thc; substrates inhibitors; carrier transporters; solute carrier ... See more keywords