Articles with "thca" as a keyword



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RNF150 suppresses thyroid carcinoma by inactivating the p38 pathway via ubiquitination of ASK1.

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Published in 2022 at "Cell biology international"

DOI: 10.1002/cbin.11786

Abstract: Thyroid carcinoma (THCA) is the most prevalent cancer in endocrine system. However, the pathogenic mechanism underlying tumor recurrence remains unclear. RING finger protein (RNF) family plays a crucial role in cancers whereas the role of… read more here.

Keywords: inactivating p38; thyroid carcinoma; rnf150; rnf150 thca ... See more keywords
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hsa_circ_0000285 facilitates thyroid cancer progression by regulating miR-127-5p/CDH2.

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Published in 2022 at "Journal of clinical laboratory analysis"

DOI: 10.1002/jcla.24421

Abstract: Thyroid cancer (THCA) is a leading endocrine cancer and becomes the fifth most commonly diagnosed malignancy in females. It is confirmed that circular RNAs (circRNAs) perform regulatory potencies in the pathological progress of THCA. Our… read more here.

Keywords: circ 0000285; thca; mir 127; hsa circ ... See more keywords
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Mesenchymal stem cells-originated exosomal microRNA-152 impairs proliferation, invasion and migration of thyroid carcinoma cells by interacting with DPP4

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Published in 2020 at "Journal of Endocrinological Investigation"

DOI: 10.1007/s40618-020-01406-2

Abstract: Thyroid carcinoma (THCA) is the most prevalent tumor in the endocrine system with an increasing incidence. Recent studies have underscored the function of microRNAs (miRNAs) in THCA. Nevertheless, knowledge regarding the effects of exosomal miRNAs… read more here.

Keywords: invasion migration; proliferation; thca; mir 152 ... See more keywords
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Affinity and Efficacy Studies of Tetrahydrocannabinolic Acid A at Cannabinoid Receptor Types One and Two

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Published in 2017 at "Cannabis and Cannabinoid Research"

DOI: 10.1089/can.2016.0032

Abstract: Abstract Introduction: Cannabis biosynthesizes Δ9-tetrahydrocannabinolic acid (THCA-A), which decarboxylates into Δ9-tetrahydrocannabinol (THC). There is growing interest in the therapeutic use of THCA-A, but its clinical application may be hampered by instability. THCA-A lacks cannabimimetic effects;… read more here.

Keywords: affinity efficacy; thca; affinity; cannabinoid receptor ... See more keywords
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Delta-9-Tetrahydrocannabinolic Acid B: A Mechanism for its Formation in Cannabis.

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Published in 2022 at "Cannabis and cannabinoid research"

DOI: 10.1089/can.2021.0216

Abstract: There appears to be consensus among Cannabis biologists that delta-9-tetrahydrocannabinolic acid A (THCA-A) is the exclusive product of the enzyme THCA synthase. This then leaves an open question for formation of the THCA-A structural isomer,… read more here.

Keywords: cannabis; acid; delta tetrahydrocannabinolic; thca ... See more keywords
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Evaluation of tetrahydrocannabinolic acid (THCA) synthase polymorphisms for distinguishing between marijuana and hemp

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Published in 2022 at "Journal of Forensic Sciences"

DOI: 10.1111/1556-4029.15045

Abstract: The Controlled Substances Act (CSA) classifies marijuana (Cannabis sativa) as a Schedule I illicit drug. However, the recent Agriculture Improvement Act of 2018 (U.S. Farm Bill) removed hemp from the definition of marijuana in the… read more here.

Keywords: crop; hemp; thca synthase; thca ... See more keywords
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Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma

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Published in 2021 at "Hereditas"

DOI: 10.1186/s41065-021-00198-6

Abstract: Background Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) has been proved to play a vital role in human cancers. Nevertheless, the exact role of ENTPD1 in thyroid carcinoma (THCA) remained unclear. This study aimed to evaluate its… read more here.

Keywords: entpd1; thca; metabolism; expression ... See more keywords
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Chemokine CCL14 affected the clinical outcome and correlated with immune infiltrates in thyroid carcinoma.

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Published in 2022 at "Histology and histopathology"

DOI: 10.14670/hh-18-548

Abstract: BACKGROUND As an important member of the chemokines, CCL14 plays a vital role in cancer progression. However, the role of CCL14 in THCA has not been investigated. This study aimed to reveal the clinical significance… read more here.

Keywords: ccl14 thca; ccl14; ccl14 immune; thca ... See more keywords
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The essential role of forkhead box P4 (FOXP4) in thyroid cancer: a study related to The Cancer Genome Atlas and experimental data

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Published in 2023 at "Endocrine Connections"

DOI: 10.1530/ec-22-0390

Abstract: Objective Thyroid cancer (THCA) is the most common endocrine cancer in the world. Although most patients with THCA have a good prognosis, the prognosis of those with THCA who have an extra-glandular invasion, vascular invasion,… read more here.

Keywords: cancer; forkhead box; thyroid cancer; thca ... See more keywords
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IncRNA TYMSOS Promotes Epithelial-Mesenchymal Transition and Metastasis in Thyroid Carcinoma through Regulating MARCKSL1 and Activating the PI3K/Akt Signaling Pathway.

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Published in 2022 at "Critical reviews in eukaryotic gene expression"

DOI: 10.1615/critreveukaryotgeneexpr.2022043838

Abstract: Thyroid carcinoma (THCA) has been increasing in incidence greater than other cancers. Long noncoding RNAs (lncRNAs) were reported to play crucial roles in THCA development. Our study aimed to explore the underlying mechanism of lncRNA… read more here.

Keywords: pi3k akt; signaling pathway; akt signaling; thca ... See more keywords
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Effect of GATAD1 regulating the SRRM2 gene on recurrence of thyroid tumor and its molecular mechanism

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Published in 2022 at "Gland Surgery"

DOI: 10.21037/gs-22-666

Abstract: Background Thyroid blood vessels and nerves are rich, and their anatomical and physiological structures are complex. Surgery often fails to eradicate the tumor, which has a serious negative impact on the surgical outcomes and patient… read more here.

Keywords: cell; gatad1 srrm2; gatad1; recurrence ... See more keywords