Platelet Count Affects Efficacy of Folic Acid in Preventing First Stroke.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.02.072
Abstract: BACKGROUND The role of platelets and important effect modifiers on the risk of first stroke is unknown. OBJECTIVES This study examined whether low platelet count (PLT) and elevated total homocysteine (tHcy) levels jointly increase the… read more here.
Keywords: folic acid; risk; first stroke; thcy ... See more keywords
Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Nutrition"
DOI: 10.1017/s0007114518002477
Abstract: Abstract We sought to examine the potential modifiers in the association between long-term low-dose folic acid supplementation and the reduction of serum total homocysteine (tHcy) among hypertensive patients, using data from the China Stroke Primary… read more here.
Keywords: folic acid; long term; thcy; effect ... See more keywords
Association of Homocysteine and Insulin Resistance with Increased Risk of Mortality in a Nondiabetic Population: Third National Health and Nutrition Examination Survey.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2021.0119
Abstract: Background and Objective: The combined effect of insulin resistance (IR) and total plasma homocysteine (tHcy) levels on the risk of mortality in nondiabetic populations has rarely been studied. We aimed to examine the association of… read more here.
Keywords: increase; risk mortality; mortality nondiabetic; mortality ... See more keywords
A1340 Elevated circulating Homocysteine and High Sensitivity C-Reactive Protein jointly as Useful Predictive Factors for Arterial Stiffness: a 12-Year Longitudinal Study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548478.64171.9b
Abstract: Objectives: Elevated plasma total homocysteine (tHcy) and high sensitivity C-reactive protein (hsCRP) levels are independent risk factors for cardiovascular disease. This study aimed to evaluate the effectiveness of tHcy and hsCRP as potential markers for… read more here.
Keywords: high sensitivity; study; thcy; hscrp ... See more keywords
Homocysteine and all-cause mortality in hypertensive adults without pre-existing cardiovascular conditions
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000005862
Abstract: Background: Previous studies support an association between elevated total homocysteine (tHcy) levels and increased all-cause mortality. However, few prospective studies have examined this association in hypertensive patients, and/or tested any effect modification by the methylene… read more here.
Keywords: cause mortality; genotype; thcy; mortality ... See more keywords
The effect of diet-induced weight loss on circulating homocysteine levels in people with obesity and type 2 diabetes
Sign Up to like & getrecommendations! Published in 2024 at "Nutrition Journal"
DOI: 10.1186/s12937-023-00908-y
Abstract: Background/aims Having type 2 diabetes (T2D) in combination with being overweight results in an additional increase in cardiovascular disease (CVD) risk. In addition, T2D and obesity are associated with increased levels of total homocysteine (tHcy),… read more here.
Keywords: weight loss; thcy; type diabetes; cvd risk ... See more keywords
Serum levels of vitamin B12 combined with folate and plasma total homocysteine predict ischemic stroke disease: a retrospective case-control study
Sign Up to like & getrecommendations! Published in 2024 at "Nutrition Journal"
DOI: 10.1186/s12937-024-00977-7
Abstract: Purpose This study aimed to identify and quantify the association and investigate whether serum vitamin B12 alone or vitamin B12 combined with folate and plasma total homocysteine (tHcy) levels could be used to predict the… read more here.
Keywords: etiology; vitamin b12; thcy; ischemic stroke ... See more keywords
Homocysteine in adult patients with cardiovascular disease: is it clinically relevant in 2025? A tribute to Hieronim Jakubowski (1946-2025).
Sign Up to like & getrecommendations! Published in 2025 at "Polish archives of internal medicine"
DOI: 10.20452/pamw.17012
Abstract: A history of persistently elevated plasma total homocysteine (tHcy) concentrations, that is, hyperhomocysteinemia, as a risk factor and/or biomarker of increased risk for cardiovascular disease (CVD) is largely based on multiple observational studies with robust… read more here.
Keywords: jakubowski; thcy; risk; cardiovascular disease ... See more keywords
Association of Elevated Plasma Total Homocysteine With Dementia With Lewy Bodies: A Case-Control Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2021.724990
Abstract: Background: Elevated plasma total homocysteine (tHcy) level, a known risk factor for vascular disease, is reported to be an independent risk factor for cognitive impairment and Alzheimer’s disease (AD) in most studies. tHcy may also… read more here.
Keywords: plasma total; dementia lewy; elevated plasma; thcy ... See more keywords
Threshold effect of plasma total homocysteine levels on cognitive function among hypertensive patients in China: A cross-sectional study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.890499
Abstract: Background Increased plasma total homocysteine (tHcy) is an influencing factor of cognitive impairment in the general population. However, studies on the relationship between the risk of cognitive impairment and plasma tHcy levels in patients with… read more here.
Keywords: among hypertensive; mmse scores; plasma thcy; thcy ... See more keywords
[The association between serum total homocysteine and subacute combined degeneration of spinal cord].
Sign Up to like & getrecommendations! Published in 2021 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20210201-00101
Abstract: Objective: The research was aimed to investigate the association between serum total homocysteine (tHcy) and subacute combined degeneration of the spinal cord (SCD). Methods: A retrospective survey of 106 newly diagnosed patients with SCD were… read more here.
Keywords: group; scd; thcy; neurology ... See more keywords