Establishment and characterization of human theca stem cells and their differentiation into theca progenitor cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27306
Abstract: In this study, we have characterized the human theca stem cells (hTSCs) and their differentiation into human theca progenitor cells (hTPCs). hTSCs were isolated from the theca layer of small antral follicles (3‐5 mm in size).… read more here.
Keywords: human theca; theca; htscs; differentiation ... See more keywords
Paeoniflorin extract reverses dexamethasone-induced testosterone over-secretion through downregulation of cytochrome P450 17A1 expression in primary murine theca cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.09.006
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Polycystic Ovarian Syndrome (PCOS) is a complex endocrine and reproductive disorder. A main hallmark includes increased androgen production. The root of Paeonia lactiflora Pall. (Bai Shao) is used in Chinese herbal medicine for… read more here.
Keywords: paeoniflorin extract; secretion; theca; theca cells ... See more keywords
Establishment of an in vitro culture model of theca cells from hierarchical follicles in ducks
Sign Up to like & getrecommendations! Published in 2017 at "Bioscience Reports"
DOI: 10.1042/bsr20160491
Abstract: Theca cells, including theca interna cells and theca externa cells, are vital components of ovarian follicles. The aim of the present study is to identify a reliable method for the in vitro culture of theca… read more here.
Keywords: phase; vitro culture; theca; theca cells ... See more keywords
Where are the theca cells from: the mechanism of theca cells derivation and differentiation
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DOI: 10.1097/cm9.0000000000000850
Abstract: Abstract Mammalian follicles are composed of oocytes, granulosa cells, and theca cells. Theca cells form in the secondary follicles, maintaining follicular structural integrity and secreting steroid hormones. Two main sources of theca cells exist: Wilms… read more here.
Keywords: cells theca; cells mechanism; theca; differentiation theca ... See more keywords
Androgen Receptor in the Ovary Theca Cells Plays a Critical Role in Androgen-Induced Reproductive Dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinology"
DOI: 10.1210/en.2016-1608
Abstract: Androgen and its receptor (AR) play a critical role in reproductive function under both physiological and pathophysiological conditions. Female AR global knockout mice are subfertile due to both neuroendocrine and ovarian defects. Female offspring from… read more here.
Keywords: androgen; theca; control; dht ... See more keywords