Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice
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DOI: 10.1038/s41467-021-23595-x
Abstract: In brown adipose tissue, thermogenesis is suppressed by thioesterase superfamily member 1 (Them1), a long chain fatty acyl-CoA thioesterase. Them1 is highly upregulated by cold ambient temperature, where it reduces fatty acid availability and limits… read more here.
Keywords: stimulus coupled; them1; superfamily member; thioesterase superfamily ... See more keywords