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Published in 2023 at "Pediatric pulmonology"
DOI: 10.1002/ppul.26445
Abstract: Cystic fibrosis (CF) has seen a multitude of therapeutic advances targeting its downstream effects. This has led to a steady increase in survival over the past few decades. The recent development of disease-modifying drugs targeting…
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Keywords:
therapeutic advances;
disparities therapeutic;
advances cystic;
cystic fibrosis ... See more keywords
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Published in 2022 at "Current Oncology Reports"
DOI: 10.1007/s11912-022-01285-1
Abstract: This article aims to bring an update on the recent discoveries in hairy cell leukemia (HCL), especially findings in pathophysiology and therapeutic advances. Major discoveries have been made in genetics and epigenetics of HCL. Moreover,…
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Keywords:
therapeutic advances;
cell leukemia;
hairy cell;
hcl ... See more keywords
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Published in 2022 at "Advances in Therapy"
DOI: 10.1007/s12325-022-02070-z
Abstract: Viral hepatitis remains a significant global health problem. All forms of viral hepatitis A through E (A–E) can lead to acute symptomatic infection, while hepatitis B and C can lead to chronic infection associated with…
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Keywords:
epidemiology;
viral hepatitis;
therapeutic advances;
curative ... See more keywords
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1
Published in 2021 at "Journal of Nephrology"
DOI: 10.1007/s40620-021-01062-6
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a heterogeneous genetic disorder included in ciliopathies, representing the fourth cause of end stage renal disease (ESRD), with an estimated prevalence between 1:1000 and 1:2500. It is mainly…
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Keywords:
nephrology;
future awaits;
cell;
therapeutic advances ... See more keywords
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Published in 2017 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2017.1377329
Abstract: ABSTRACT Despite great success in the development of curative therapies for pediatric hematologic malignancies, new approaches are needed to overcome resistance to treatment and to reduce associated side effects. The Therapeutic Advances in Childhood Leukemia…
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Keywords:
childhood leukemia;
advances childhood;
hematology;
therapeutic advances ... See more keywords
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Published in 2017 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2017.1395937
Abstract: ABSTRACT During the 2016 Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium investigators' meeting (Los Angeles, CA), a Biology Working Group was established to support the consortium's mission of developing innovative therapies for currently…
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Keywords:
consortium;
working group;
therapeutic advances;
biology working ... See more keywords
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Published in 2022 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000873
Abstract: Purpose of review In recent years, therapeutic advances in eosinophilic granulomatosis with polyangiitis (EGPA) have changed our treatment paradigm. This review will summarize and discuss updates in management of EGPA, with a particular focus on…
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Keywords:
granulomatosis polyangiitis;
therapeutic advances;
eosinophilic granulomatosis;
advances eosinophilic ... See more keywords
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Published in 2019 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000000559
Abstract: Purpose of review The aim of this review is to highlight recent changes in the treatment of juvenile idiopathic arthritis (JIA) – associated uveitis in the era of biologics. Recent findings Early introduction of steroid-sparing…
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Keywords:
jia uveitis;
therapeutic advances;
juvenile idiopathic;
associated uveitis ... See more keywords
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Published in 2019 at "American Journal of Therapeutics"
DOI: 10.1097/mjt.0000000000001034
Abstract: BACKGROUND The International Myeloma Working Group has defined smoldering multiple myeloma (SMM) as the presence of 10%-60% plasma cells in the bone marrow and M-protein (IgG, IgA) ≥3 g/dL without end-organ damage (an increased calcium…
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Keywords:
myeloma;
therapeutic advances;
advances management;
multiple myeloma ... See more keywords
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Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0903-0
Abstract: Thyroid cancer incidence is increasing at an alarming rate, almost tripling every decade. In 2017, it was the fifth most common cancer in women. Although the majority of thyroid tumors are curable, about 2–3% of…
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Keywords:
cancer current;
anaplastic thyroid;
therapeutic advances;
thyroid cancer ... See more keywords
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Published in 2018 at "Arquivos de neuro-psiquiatria"
DOI: 10.1590/0004-282x20180011
Abstract: Spinal muscular atrophy (SMA) is a severe and clinically-heterogeneous motor neuron disease caused, in most cases, by a homozygous mutation in the SMN1 gene. Regarding the age of onset and motor involvement, at least four…
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Keywords:
advances linked;
therapeutic advances;
spinal muscular;
linked spinal ... See more keywords