Exosomes as a novel cell‐free therapeutic approach in gastrointestinal diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27934
Abstract: Cell communication through extracellular vesicles (EVs) has been defined for many years and it is not limited only to neighboring cells, but also distant ones in organisms receive these signals. These vesicles are secreted from… read more here.
Keywords: gastrointestinal diseases; free therapeutic; cell free; approach gastrointestinal ... See more keywords
A New Therapeutic Approach to Obesity: Stroke?
Sign Up to like & getrecommendations! Published in 2017 at "Obesity Surgery"
DOI: 10.1007/s11695-017-2604-y
Abstract: Obesity was declared a global health epidemic in 2003 by the World Health Organization. Control of eating in the human brain is provided by several neural systems. Decision-making and cognitive control (prefrontal cortex, cingulate), food… read more here.
Keywords: approach obesity; control; obesity stroke; new therapeutic ... See more keywords
Targeting AMPK by Statins: A Potential Therapeutic Approach
Sign Up to like & getrecommendations! Published in 2021 at "Drugs"
DOI: 10.1007/s40265-021-01510-4
Abstract: Statins are a group of lipid-lowering drugs that inhibit cholesterol biosynthesis and have anti-inflammatory, anti-tumor, and immunomodulatory properties. Several lines of evidence indicate that statins regulate multiple proteins associated with the regulation of differing cellular… read more here.
Keywords: therapeutic approach; targeting ampk; therapeutic effects; ampk statins ... See more keywords
Autoimmune bullous diseases in pregnancy: clinical and epidemiological characteristics and therapeutic approach
Sign Up to like & getrecommendations! Published in 2021 at "Anais Brasileiros de Dermatologia"
DOI: 10.1016/j.abd.2020.10.007
Abstract: Autoimmune bullous dermatoses are a heterogeneous group of diseases with autoantibodies against structural skin proteins. Although the occurrence of autoimmune bullous dermatoses during pregnancy is low, this topic deserves attention, since the immunological and hormonal… read more here.
Keywords: bullous dermatoses; diseases pregnancy; autoimmune bullous; bullous diseases ... See more keywords
Psoriasis in the mature patient: Therapeutic approach in the era of biologics.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics in dermatology"
DOI: 10.1016/j.clindermatol.2017.10.013
Abstract: Management of psoriasis in elderly patients may be challenging due to a small number of studies investigating this specific population. When treating a mature patient, special consideration should be given to multiple comorbidities, progressive functional… read more here.
Keywords: mature patient; psoriasis mature; psoriasis; population ... See more keywords
Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104591
Abstract: Idiopathic pulmonary fibrosis (IPF) is a debilitating condition where excess collagen deposition occurs in the extracellular matrix. At first sight, it is expected that the level of different kinds of matrix metalloproteinases might be downregulated… read more here.
Keywords: fibrosis; idiopathic pulmonary; matrix; pulmonary fibrosis ... See more keywords
Antiviral properties of placental growth factors: A novel therapeutic approach for COVID-19 treatment
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.07.033
Abstract: Abstract The current challenge of the COVID-19 pandemic is complicated by the limited therapeutic options against the virus, with many being anecdotal or still undergoing confirmatory trials, underlining the urgent need for novel strategies targeting… read more here.
Keywords: treatment; growth factors; covid; approach ... See more keywords
Emetophobia - A Metacognitive Therapeutic Approach for an Overlooked Disorder.
Sign Up to like & getrecommendations! Published in 2018 at "Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie"
DOI: 10.1024/1422-4917/a000464
Abstract: Objective Emetophobia is the specific fear of vomiting that usually commences during childhood and adolescence. Cognitive behavioral therapy aims to expose patients to vomiting. In this paper, a newly developed metacognitive concept and treatment approach… read more here.
Keywords: emetophobia; emetophobia metacognitive; disorder; therapeutic approach ... See more keywords
Stabilin-1-Mediated Efferocytosis Protects against Vascular Leakage in Sepsis: A Novel Therapeutic Approach?
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0038-1673688
Abstract: Sepsis is a complex clinical syndrome with high lethality characterized by systemic inflammation and organ failure.1 Although intensive research over the past decades has identified several mechanisms contributing to sepsis pathology, sepsis represents a major… read more here.
Keywords: sepsis; stab; efferocytosis; vascular leakage ... See more keywords
Nutraceuticals-based therapeutic approach: recent advances to combat pathogenesis of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2021.1923479
Abstract: ABSTRACT Introduction: Alzheimer’s disease (AD) is a progressive neurodegenerative disease accompanying memory deficits. The available pharmaceutical care has some limitations mostly entailing side effects, shelf-life, and patient’s compliance. The momentous implications of nutraceuticals in AD… read more here.
Keywords: alzheimer disease; disease; nutraceuticals based; based therapeutic ... See more keywords
Therapeutic approach to neurological manifestations of Angelman syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2109463
Abstract: ABSTRACT Introduction Angelman syndrome (AS) is a neurogenetic disorder due to deficient expression of the maternal copy of the UBE3A gene, which encodes ubiquitin ligase E3A protein. Severe developmental delay, seizures and other neurological disorders… read more here.
Keywords: manifestations angelman; approach neurological; neurological manifestations; therapeutic approach ... See more keywords