Pathogenesis and prospects for therapeutic clinical application of noncoding RNAs in glaucoma: Systematic perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30347
Abstract: Noncoding ribonucleic acids (ncRNAs) are an increasingly studied class of RNA molecules with extensive biological activities, including important roles in human development, health, and disease. Glaucoma is a neurodegenerative disease of the retina, and one… read more here.
Keywords: pathogenesis prospects; prospects therapeutic; glaucoma; noncoding rnas ... See more keywords
The underreporting of phase III chemo-therapeutic clinical trial data of older patients with cancer: A systematic review.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2019.12.007
Abstract: PURPOSE Inspired by the American Society of Clinical Oncology's recommendations to strengthen the evidence base for older adults with cancer, the purpose of this systematic review is to identify the reporting of treatment efficacy and… read more here.
Keywords: age; chemo therapeutic; review; cancer ... See more keywords
Aiming for protective T-cell responses: a focus on the first generation conserved-region HIVconsv vaccines in preventive and therapeutic clinical trials
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2019.1675518
Abstract: ABSTRACT Introduction: Despite life-saving antiretroviral drugs, an effective HIV-1 vaccine is the best solution and likely a necessary component of any strategy for halting the AIDS epidemic. The currently prevailing aim is to pursue antibody-mediated… read more here.
Keywords: first generation; generation conserved; conserved region; clinical trials ... See more keywords
Communication Regarding Therapeutic Clinical Trial Enrollment Between Oncologists and Adolescents and Young Adults with Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of adolescent and young adult oncology"
DOI: 10.1089/jayao.2019.0107
Abstract: Adolescent and young adult (AYA) cancer patients enroll in therapeutic clinical trials at low rates. Prior study has focused on trial availability; this research attempts to elucidate the role of communication in individual decision-making. We… read more here.
Keywords: trial; communication; regarding therapeutic; communication regarding ... See more keywords
Defining the Threshold of Permissible Risk for Non-therapeutic Clinical Trials with Children in Europe
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DOI: 10.1163/15718093-12341420
Abstract: It is important that clinical research with children is encouraged so that they are not exposed to the dangers of extrapolation from adult treatments. Clinical trials with investigational medicinal products (IMPs) are an important part… read more here.
Keywords: non therapeutic; clinical trials; defining threshold; risk non ... See more keywords