Molecular Insights into Therapeutic Potentials of Hybrid Compounds Targeting Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02779-6
Abstract: Alzheimer's disease (AD) is one of the most complex progressive neurological disorders involving degeneration of neuronal connections in brain cells leading to cell death. AD is predominantly detected among elder people (> 65 years), mostly diagnosed with… read more here.
Keywords: therapeutic compounds; hybrid compounds; hybrid molecules; molecular insights ... See more keywords
Therapeutic compounds from medicinal plant endophytes: molecular and metabolic adaptations.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of applied microbiology"
DOI: 10.1093/jambio/lxad074
Abstract: During the last few decades, endophytes have attracted increased attention due to their ability to produce a plethora of bioactive secondary metabolites. These compounds not only help the endophytes to outcompete other plant-associated microbes or… read more here.
Keywords: compounds medicinal; plant endophytes; medicinal plant; endophytes molecular ... See more keywords
Therapeutic compounds targeting Lipid II for antibacterial purposes
Sign Up to like & getrecommendations! Published in 2019 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s215070
Abstract: Abstract Resistance against commonly used antibiotics has emerged in all bacterial pathogens. In fact, there is no antibiotic currently in clinical use against which resistance has not been reported. In particular, rapidly increasing urbanization in… read more here.
Keywords: targeting lipid; resistance; therapeutic compounds; cell wall ... See more keywords
KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Current Neuropharmacology"
DOI: 10.2174/1570159x15666170630164226
Abstract: Background The intermediate-conductance Ca2+-activated K+ channel KCa3.1 is widely expressed in cells of the immune system such as T- and B-lymphocytes, mast cells, macrophages and microglia, but also found in dedifferentiated vascular smooth muscle cells,… read more here.
Keywords: channel modulators; kca3 channel; compounds glioblastoma; therapeutic compounds ... See more keywords
Transdermal Delivery of Therapeutic Compounds With Nanotechnological Approaches in Psoriasis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.804415
Abstract: Psoriasis is a chronic, immune-mediated skin disorder involving hyperproliferation of the keratinocytes in the epidermis. As complex as its pathophysiology, the optimal treatment for psoriasis remains unsatisfactorily addressed. Though systemic administration of biological agents has… read more here.
Keywords: delivery therapeutic; therapeutic compounds; transdermal delivery; drug ... See more keywords
Identification of the Key Genes and Potential Therapeutic Compounds for Abdominal Aortic Aneurysm Based on a Weighted Correlation Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10051052
Abstract: Background: There is still an unmet need for therapeutic drugs for patients with an abdominal aortic aneurysm (AAA), especially for candidates unsuitable for surgical or interventional repair. Therefore, the purpose of this in silico study… read more here.
Keywords: hub genes; hub; analysis; therapeutic compounds ... See more keywords
A Review of Synthetic Access to Therapeutic Compounds Extracted from Psilocybe
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph16010040
Abstract: Psychedelics are used for various pathologies of the central nervous system and are currently the subject of much research, some of which relates to the compounds contained in various Psilocybe-type hallucinogenic mushrooms. It is difficult,… read more here.
Keywords: access therapeutic; synthetic access; review synthetic; therapeutic compounds ... See more keywords