New therapeutic concepts in bile acid transport and signaling for management of cholestasis
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28991
Abstract: The identification of the key regulators of bile acid (BA) synthesis and transport within the enterohepatic circulation has revealed potential targets for pharmacological therapies of cholestatic liver diseases. Novel drug targets include the bile BA… read more here.
Keywords: transport signaling; transport; new therapeutic; therapeutic concepts ... See more keywords
Post-transcriptional control of hemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders.
Sign Up to like & getrecommendations! Published in 2023 at "Cardiovascular research"
DOI: 10.1093/cvr/cvad046
Abstract: The hemostatic system is pivotal to maintaining vascular integrity. Multiple components involved in blood coagulation have central functions in inflammation and immunity. A derailed hemostasis is common in prevalent pathologies such as sepsis, cardiovascular disorders… read more here.
Keywords: system; transcriptional control; therapeutic concepts; hemostatic system ... See more keywords
Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts
Sign Up to like & getrecommendations! Published in 2017 at "Viruses"
DOI: 10.3390/v9050095
Abstract: The hepatitis B virus (HBV) infects hepatocytes, which are the main cell type composing a human liver. However, the liver is enriched with immune cells, particularly innate cells (e.g., myeloid cells, natural killer and natural… read more here.
Keywords: innate immunity; therapeutic concepts; hbv; hepatitis virus ... See more keywords