A comparison between pure active pharmaceutical ingredients and therapeutic deep eutectic solvents: Solubility and permeability studies
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.02.003
Abstract: &NA; THEDES, so called therapeutic deep eutectic solvents are here defined as a mixture of two components, which at a particular molar composition become liquid at room temperature and in which one of them is… read more here.
Keywords: system; permeability; deep eutectic; solubility ... See more keywords
Development of Polycaprolactone-Based Metronidazole Matrices for Intravaginal Extended Drug Delivery Using a Mechanochemically Prepared Therapeutic Deep Eutectic System.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120071
Abstract: The engineering of crystalline multi-component drug systems, including cocrystals and salts, is now an established method of modifying the physicochemical properties and dissolution behaviour of an active ingredient. Remarkably, liquid drug systems, including therapeutic ionic… read more here.
Keywords: delivery; development polycaprolactone; drug; deep eutectic ... See more keywords
Design of Functional Therapeutic Deep Eutectic Solvents Based on Choline Chloride and Ascorbic Acid
Sign Up to like & getrecommendations! Published in 2018 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.8b01687
Abstract: In this work, we report the preparation of novel therapeutic deep eutectic solvents (THEDES) based on choline chloride (CC) and ascorbic acid (AA), in which dexamethasone (DEX) was successfully solubilized. THEDES were synthesized and characterized… read more here.
Keywords: choline chloride; dex; based choline; deep eutectic ... See more keywords
Therapeutic deep brain stimulation worsening dysprosody in Parkinson’s disease – an unexplored entity
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s160803
Abstract: and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove… read more here.
Keywords: neuropsychiatric disease; deep brain; disease; therapeutic deep ... See more keywords