Recent Advances of DNA Tetrahedra for Therapeutic Delivery and Biosensing
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202000835
Abstract: The chemical and self‐assembly properties of nucleic acids make them ideal for the construction of discrete structures and stimuli‐responsive devices for a diverse array of applications. Amongst the various three‐dimensional assemblies, DNA tetrahedra are of… read more here.
Keywords: dna tetrahedra; therapeutic delivery; recent advances; advances dna ... See more keywords
Layer-by-Layer Engineered Polymer Capsules for Therapeutic Delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7741-3_6
Abstract: Polymer capsules fabricated via layer-by-layer (LbL) assembly have emerged as promising carriers for therapeutic delivery. The versatile assembly technique allows an extensive choice of materials to be incorporated as constituents of the multilayers, which therefore… read more here.
Keywords: layer; delivery; therapeutic delivery; layer layer ... See more keywords
Combinatorial approaches in post-polymerization modification for rational development of therapeutic delivery systems.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.04.010
Abstract: The combinatorial polymer library approach has been proven to be effective for the optimization of therapeutic delivery systems. The library of polymers with chemical diversity has been synthesized by (i) polymerization of functionalized monomers or… read more here.
Keywords: post polymerization; polymerization; delivery; therapeutic delivery ... See more keywords
Enrichment of cellulose acetate nanofibre assemblies for therapeutic delivery of l-tryptophan.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.11.124
Abstract: The essential amino acid l-tryptophan is naturally present in the body, and is also available as a water soluble dietary supplement. The feasibility of preparing enriched cellulose acetate (CA)-based fibres as a vehicle for therapeutic… read more here.
Keywords: delivery; therapeutic delivery; tryptophan; enrichment cellulose ... See more keywords
Engineering Self-Assembling Protein Nanoparticles for Therapeutic Delivery
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate Chemistry"
DOI: 10.1021/acs.bioconjchem.2c00030
Abstract: Despite remarkable advances over the past several decades, many therapeutic nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity, optimizing biodistribution, and engineering environmental responsiveness are key outstanding delivery problems for most nanotherapeutics.… read more here.
Keywords: therapeutic delivery; assembling protein; protein nanoparticles; self assembling ... See more keywords
Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: From design to therapeutic applications.
Sign Up to like & getrecommendations! Published in 2020 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.9b01754
Abstract: Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential to offer cures for previously untreatable diseases. However, they present an enormous delivery challenge due to… read more here.
Keywords: protein nucleic; delivery; therapeutic delivery; polymersomes therapeutic ... See more keywords
Therapeutic Delivery of Nitric Oxide Utilizing Saccharide-Based Materials.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c10964
Abstract: As a gasotransmitter, nitric oxide (NO) regulates physiological pathways and demonstrates therapeutic effects such as vascular relaxation, anti-inflammation, antiplatelet, antithrombosis, antibacterial, and antiviral properties. However, gaseous NO has high reactivity and a short half-life, so… read more here.
Keywords: nitric oxide; therapeutic delivery; saccharide based; based materials ... See more keywords
One-Step Fabrication of Hollow Spherical Cellulose Beads: Application in pH-Responsive Therapeutic Delivery
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.1c19577
Abstract: The path to greater sustainability and the development of polymeric drug delivery systems requires innovative approaches. The adaptation and use of biobased materials for applications such as targeted therapeutic delivery is, therefore, in high demand.… read more here.
Keywords: therapeutic delivery; spherical cellulose; fabrication hollow; hollow spherical ... See more keywords
Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery
Sign Up to like & getrecommendations! Published in 2018 at "Nature chemistry"
DOI: 10.1038/nchem.2917
Abstract: The successful transport of drug- and cell-based therapeutics to diseased sites represents a major barrier in the development of clinical therapies. Targeted delivery can be mediated through degradable biomaterial vehicles that utilize disease biomarkers to… read more here.
Keywords: biomaterial logic; delivery; therapeutic delivery; modular biomaterial ... See more keywords
The Shape Effect on Polymer Nanoparticle Transport in a Blood Vessel.
Sign Up to like & getrecommendations! Published in 2018 at "RSC advances"
DOI: 10.1039/c8ra00033f
Abstract: Nanoparticle therapeutic delivery is influenced by many factors including physical, chemical, and biophysical properties along with local vascular conditions. In recent years, nanoparticles of various shapes have been fabricated and have shown significant impact on… read more here.
Keywords: rod nanoparticles; delivery; therapeutic delivery; nanoparticle ... See more keywords
Enhancing Therapeutic Delivery Using Micro- and Nanorobots
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Pulse"
DOI: 10.1109/mpuls.2023.3269754
Abstract: “The traditional way of delivering drugs has a very low efficiency. For instance, with solid tumors, drug delivery efficiency is reported to be lower than 1% [1], which means that 99% of the drug is… read more here.
Keywords: therapeutic delivery; delivery using; using micro; enhancing therapeutic ... See more keywords