Use of a neural network-based prediction method to calculate the therapeutic dose in boron neutron capture therapy of patients with glioblastoma.
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16215
Abstract: BACKGROUND Boron neutron capture therapy (BNCT) is a binary radiotherapy based on the 10 B(n, α)7 Li capture reaction. Nonradioactive isotope 10 B atoms which selectively concentrated in tumor cells will react with low energy… read more here.
Keywords: therapeutic dose; patients glioblastoma; prediction method; method ... See more keywords
Combination of metformin and sub-therapeutic dose of valproic acid prevent valproic acid-induced toxicity in animal model of epilepsy.
Sign Up to like & getrecommendations! Published in 2023 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2023.2168689
Abstract: Valproic acid (VPA) is one of the most prescribed drugs for epilepsy. Extended use of VPA not only induces hepatotoxicity but also impairs the cognitive functions. Metformin has been reported to prevent epileptogenesis and enhance… read more here.
Keywords: combination; therapeutic dose; valproic acid; sub therapeutic ... See more keywords
The Effectiveness of the Intermediate and Therapeutic Doses of Enoxaparin in COVID-19 Patients: A Comparative Study of Factor Xa Inhibition
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DOI: 10.1159/000528736
Abstract: Background: Management of anticoagulant therapy in COVID-19 patients is critical. Low-molecular-weight heparin (LMWH) thromboprophylaxis is already recommended, and anti-Factor Xa (anti-FXa) monitoring has been used to titrate LMWH doses. Methods: Through a cross-sectional study, we… read more here.
Keywords: dose group; dose; anti fxa; therapeutic dose ... See more keywords
Prophylactic versus therapeutic dose anticoagulation effects on survival among critically ill patients with COVID-19
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DOI: 10.1371/journal.pone.0262811
Abstract: Introduction Although patients with severe COVID-19 are known to be at high risk of developing thrombotic events, the effects of anticoagulation (AC) dose and duration on in-hospital mortality in critically ill patients remain poorly understood… read more here.
Keywords: ill patients; critically ill; therapeutic dose; risk ... See more keywords
Therapeutic Dose of Hydroxyurea-Induced Synaptic Abnormalities on the Mouse Spermatocyte
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.666339
Abstract: Hydroxyurea (HU) is a widely used pharmacological therapy for sickle cell disease (SCD). However, replication stress caused by HU has been shown to inhibit premeiotic S-phase DNA, leading to reproductive toxicity in germ cells. In… read more here.
Keywords: therapeutic dose; induced synaptic; dose hydroxyurea; hydroxyurea ... See more keywords
Hepatic failure with fatal outcome during pregnancy following administration of a single therapeutic dose of acetominophen: Case report and literature review.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp204242
Abstract: Acetaminophen is generally regarded as a safe antipyretic and analgetic agent and is widely used in cases of pregnancy. However, acetaminophen is also one of the most frequently reported medications in cases of drug overdose.… read more here.
Keywords: outcome pregnancy; failure; report; therapeutic dose ... See more keywords