Oligoethyleneimine‐Conjugated Hyaluronic Acid Modulates Inflammatory Responses and Enhances Therapeutic Efficacy for Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202100548
Abstract: Modulation of innate immune responses is a potential strategy for treating inflammatory diseases. Although biogenic polyamines are known as immunomodulatory compounds possessing anti‐inflammatory functions, their biomedical applications have been limited owing to their cytotoxicity. Here,… read more here.
Keywords: therapeutic efficacy; hyaluronic acid; inflammatory responses; ulcerative colitis ... See more keywords
Interleukin-4 Gene Transfection and Spheroid Formation Potentiate Therapeutic Efficacy of Mesenchymal Stem Cells for Osteoarthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901612
Abstract: Osteoarthritis (OA) is a painful intractable disease that significantly affects patients' quality of life. However, current therapies, such as pain killers and joint replacement surgery, do not lead to cartilage protection. Mesenchymal stem cells (MSCs)… read more here.
Keywords: potentiate therapeutic; therapeutic efficacy; mscs; stem cells ... See more keywords
Therapeutic efficacy of FASN inhibition in preclinical models of HCC.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32359
Abstract: BACKGROUND & AIMS Aberrant activation of fatty acid synthase (FASN) is a major metabolic event during the development of HCC. We evaluated the therapeutic efficacy of TVB3664, a novel FASN inhibitor, either alone or in… read more here.
Keywords: hcc treatment; tvb3664; efficacy fasn; therapeutic efficacy ... See more keywords
Evaluating the Therapeutic Efficacy of Radiolabeled BSA@CuS Nanoparticle-induced Radio-photothermal Therapy against Anaplastic Thyroid Cancer.
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DOI: 10.1002/iub.2601
Abstract: PURPOSE Bovine serum albumin (BSA) has been employed as a mild biological template in nanoscale particles. Copper sulfide (CuS) has been used for photothermal therapy (PTT) in several studies. In this study, we aimed to… read more here.
Keywords: photothermal therapy; therapeutic efficacy; cus; bsa cus ... See more keywords
Therapeutic efficacy of orally administered pollen for nonallergic diseases: An umbrella review
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DOI: 10.1002/ptr.6484
Abstract: Pollen has been used for centuries as a tonic and a multipurpose remedy in traditional medicine. The present umbrella review aims to qualitatively assess the therapeutic efficacy of orally administered pollen in the management of… read more here.
Keywords: umbrella review; therapeutic efficacy; evidence; review ... See more keywords
Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16+ cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-03134-9
Abstract: Human papilloma virus (HPV) infection is a causative agent for several cancers types (genital, anal and head and neck region). The HPV E6 and E7 proteins are oncogenic drivers and thus are ideal candidates for… read more here.
Keywords: rna lpx; hpv16 cancer; rna; therapeutic efficacy ... See more keywords
Therapeutic efficacy of chloroquine for the treatment of Plasmodium vivax malaria among outpatients at Shawa Robit Health Care Centre, North-East Ethiopia.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.02.027
Abstract: Nearly 40% of all malaria infection in Ethiopia is caused by Plasmodium vivax. Chloroquine (CQ) is the first line treatment for confirmed P. vivax malaria in the country. However, the efficacy of this drug has… read more here.
Keywords: vivax malaria; therapeutic efficacy; study; vivax ... See more keywords
Therapeutic efficacy of modified anti-miR21 in metastatic prostate cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.215
Abstract: Despite improved therapeutic efficacy of the locked nucleic acid (LNA)- and peptide nucleic acid (PNA)-modified antisense microRNAs (anti-miRs), their wider application in clinical practice is still not thoroughly investigated. This study aimed to investigate the… read more here.
Keywords: cancer; anti mir21; mir21; therapeutic efficacy ... See more keywords
Polyglycerolated nanocarriers with increased ligand multivalency for enhanced in vivo therapeutic efficacy of paclitaxel.
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DOI: 10.1016/j.biomaterials.2017.08.042
Abstract: Despite the excellent biocompatibility and antifouling effect of poly(ethylene glycol) (PEG), the high steric hindrance, limited chemical functionality, and low ligand multivalency of PEGylated nanocarriers often lead to inefficient cell targeting and intracellular trafficking. Hence,… read more here.
Keywords: ligand multivalency; therapeutic efficacy; ligand; vivo therapeutic ... See more keywords
2D and 3D co-spatial compartmentalized patch to enhance the therapeutic efficacy of keratinocytes for wound closure
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DOI: 10.1016/j.cej.2020.128130
Abstract: Abstract Keratinocytes are frequently used for the biological and biomedical remodeling of damaged skin tissues. However, low cell viability, poor cell maintenance, and lack of paracrine factors hamper the therapeutic efficacy of keratinocytes for skin… read more here.
Keywords: efficacy keratinocytes; wound closure; therapeutic efficacy; efficacy ... See more keywords
Therapeutic efficacy of a paclitaxel-loaded nanofibrillated bacterial cellulose (PTX/NFBC) formulation in a peritoneally disseminated gastric cancer xenograft model.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.01.201
Abstract: Nano-fibrillated bacterial cellulose (NFBC) is a safe, biocompatible material that can be prepared by culturing a cellulose-producing bacterium in a culture supplemented with carboxymethylcellulose (CMC) or hydroxypropylcellulose (HPC). CM-NFBC and HP-NFBC, prepared using CMC or… read more here.
Keywords: disseminated gastric; cellulose; ptx; therapeutic efficacy ... See more keywords