Transcriptomic Analysis in Human Macrophages Infected with Therapeutic Failure Clinical Isolates of Leishmania infantum
Sign Up to like & getrecommendations! Published in 2022 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.1c00513
Abstract: Leishmaniasis is one of the neglected tropical diseases with a worldwide distribution, affecting humans and animals. In the absence of an effective vaccine, current treatment is through the use of chemotherapy; however, existing treatments have… read more here.
Keywords: leishmania infantum; analysis human; analysis; therapeutic failure ... See more keywords
Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria.
Sign Up to like & getrecommendations! Published in 2019 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0163-2019
Abstract: Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan… read more here.
Keywords: artemether lumefantrine; three cases; therapy; combination therapy ... See more keywords
Achievement of Target Serum Uric Acid Levels and Factors Associated with Therapeutic Failure among Japanese Men Treated for Hyperuricemia/Gout
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DOI: 10.2169/internalmedicine.1899-18
Abstract: Objective To assess the rate of successfully achieving treatment goals among Japanese men with hyperuricemia/gout and identify factors influencing the success rate. Methods This cross-sectional study, conducted from January to December 2012, examined the serum… read more here.
Keywords: sua levels; hyperuricemia gout; failure; therapeutic failure ... See more keywords
The miRNA 361-3p, a Regulator of GZMB and TNF Is Associated With Therapeutic Failure and Longer Time Healing of Cutaneous Leishmaniasis Caused by L. (viannia) braziliensis
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DOI: 10.3389/fimmu.2018.02621
Abstract: L. (viannia) braziliensis infection causes American Tegumentary Leishmaniasis (ATL), with prolonged time to healing lesions. The potent inflammatory response developed by the host is important to control the parasite burden and infection however an unbalanced… read more here.
Keywords: leishmaniasis; mir 361; braziliensis; time ... See more keywords