EXTH-38. ENGINEERED EXOSOMES FOR THERAPEUTIC GENE DELIVERY IN BRAIN TUMORS
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.370
Abstract: The poor outcome of patients with glioblastoma (GBM) is at least partly due to the inability to deliver therapeutic agents to the tumor. We have shown that exosomes, naturally occurring nano-size extracellular vesicles, are capable… read more here.
Keywords: therapeutic gene; engineered exosomes; delivery; brain tumors ... See more keywords
Therapeutic Gene Editing in Inherited Retinal Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041292
Abstract: Since the development of CRISPR/Cas9 gene editing in 2012, therapeutic editing research has produced several phase 1-2a trials. Here we provide an overview of the mechanisms and applications of various gene-editing technologies including adeno-associated virus… read more here.
Keywords: editing inherited; gene editing; therapeutic gene; inherited retinal ... See more keywords