Articles with "therapeutic levels" as a keyword



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Commentary on “High incidence of persistent sub-therapeutic levels of most common AEDs in children with epilepsy receiving polypharmacy”

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Published in 2018 at "Epilepsy Research"

DOI: 10.1016/j.eplepsyres.2018.09.010

Abstract: The paper by Czornyj et al. accepts the hypothesis that non-compliance/non-adherence to a therapeutic regimen may well explain the presence of low antiepileptic medication (AEM) blood levels in ambulatory patients but does not accept this… read more here.

Keywords: sub therapeutic; high incidence; commentary high; incidence persistent ... See more keywords

Tailoring pediatric vancomycin doses: achieving therapeutic levels and minimizing toxicity in oncology patients.

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Published in 2025 at "Personalized medicine"

DOI: 10.1080/17410541.2025.2565143

Abstract: BACKGROUND Vancomycin is a widely used nephrotoxic drug in pediatric oncology. Our aim was to assess the initial vancomycin dosing protocols required for achieving the target therapeutic concentrations of vancomycin between 10 and 20 mcg/ml.… read more here.

Keywords: oncology; oncology patients; therapeutic levels; toxicity ... See more keywords

Effect of Ethnicity on Tacrolimus (Adoport) Trough Concentrations in Renal Transplant Recipients. A Single Centre Retrospective Study

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Published in 2018 at "Transplantation"

DOI: 10.1097/01.tp.0000543472.72552.71

Abstract: Introduction Calcineurin-inhibitors (CNI) have a narrow therapeutic window and warrant close therapeutic dose monitoring (TDM). CNI metabolism and consequently its serum trough concentrations (C0) depend on multiple factors, one of which is ethnicity. This prompted… read more here.

Keywords: black patients; adoport; transplantation; renal transplant ... See more keywords