Targets for MAbs: innovative approaches for their discovery & validation, LabEx MAbImprove 6th antibody industrial symposium, June 25-26, 2018, Montpellier, France
Sign Up to like & getrecommendations! Published in 2019 at "mAbs"
DOI: 10.1080/19420862.2019.1612691
Abstract: ABSTRACT Monoclonal antibodies (mAbs) have revolutionized the treatment landscape in many disciplines of human medicine. To continue this exciting trend, sustained identification of new, validated and preferably functional targets are needed. However, this is the… read more here.
Keywords: targets mabs; symposium; labex mabimprove; therapeutic mabs ... See more keywords
Crystallizable Fragment Glycoengineering for Therapeutic Antibodies Development
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01554
Abstract: Monoclonal antibody (mAb)-based therapeutics are the fastest growing class of human pharmaceuticals. They are typically IgG1 molecules with N-glycans attached to the N297 residue on crystallizable fragment (Fc). Different Fc glycoforms impact their effector function,… read more here.
Keywords: therapeutic antibodies; crystallizable fragment; fragment glycoengineering; glycoengineering therapeutic ... See more keywords