The therapeutic mavericks: Potent immunomodulating chaperones capable of treating human diseases
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DOI: 10.1111/jcmm.17669
Abstract: Two major chaperones, calreticulin (CRT) and binding immunoglobulin protein (GRP78/BiP) dependent on their location, have immunoregulatory or anti‐inflammatory functions respectively. CRT induces pro‐inflammatory cytokines, dendritic cell (DC) maturation and activates cytotoxic T cells against tumours.… read more here.
Keywords: crt; cell; grp78 bip; therapeutic mavericks ... See more keywords