GW29-e0366 An Exploration of Therapeutic Mechanism of Lingguizhugan Decoction in Chronic Heart Failure Based on Network Pharmacology
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.052
Abstract: Lingguizhugan decoction (LGZGD), a well-known traditional Chinese medicine (TCM) formula has been widely using in modern clinical practice to treat various cardiovascular disease, especially in chronic heart failure (CHF). However, the underlying therapeutic mechanism is not… read more here.
Keywords: therapeutic mechanism; heart failure; pharmacology; lingguizhugan decoction ... See more keywords
Ketamine for post-traumatic stress disorders and it's possible therapeutic mechanism
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2021.105044
Abstract: Posttraumatic stress disorder (PTSD) is a devastating medical illness, for which currently available pharmacotherapies have poor efficacy. Accumulating evidence from clinical and preclinical animal investigations supports that ketamine exhibits a rapid and persistent effect against… read more here.
Keywords: mechanism; therapeutic mechanism; ketamine; mechanism ketamine ... See more keywords
Investigating the Therapeutic Mechanism of Cannabidiol in a Human Induced Pluripotent Stem Call (iPSC)-Based Cellular Model of Dravet Syndrome.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor symposia on quantitative biology"
DOI: 10.1101/sqb.2018.83.038174
Abstract: Dravet syndrome is an infantile epileptic encephalopathy primarily caused by loss-of-function variants of the gene SCN1A Standard treatment regimens have very limited efficacy to combat the life-threatening seizures in Dravet syndrome or the behavioral-cognitive comorbidities… read more here.
Keywords: mechanism; model dravet; therapeutic mechanism; cellular model ... See more keywords
Phosphorylation‐mediated PI3K‐Art signalling pathway as a therapeutic mechanism in the hydrogen‐induced alleviation of brain injury in septic mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17568
Abstract: Our previous studies illustrated that 2% H2 inhalation can protect against sepsis‐associated encephalopathy (SAE) which is characterized by high mortality and has no effective treatment. To investigate the underlying role of protein phosphorylation in SAE… read more here.
Keywords: phosphorylation mediated; brain; phosphorylation; signalling pathway ... See more keywords
Multi-omics approaches for in-depth understanding of therapeutic mechanism for Traditional Chinese Medicine
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1031051
Abstract: Traditional Chinese Medicine (TCM) is extensively utilized in clinical practice due to its therapeutic and preventative treatments for various diseases. With the development of high-throughput sequencing and systems biology, TCM research was transformed from traditional… read more here.
Keywords: multi omics; medicine; tcm; therapeutic mechanism ... See more keywords
Therapeutic mechanism of Curcuma aromatica Salisb. rhizome against coronary heart disease based on integrated network pharmacology, pharmacological evaluation and lipidomics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.950749
Abstract: Curcuma aromatica Salisb. rhizome (CASR) has multifunctional characteristics worldwide and a long history of use as a botanical drug with. Currently, it is often used clinically to treat coronary heart disease (CHD) caused by blood… read more here.
Keywords: curcuma aromatica; pharmacology; casr; chd ... See more keywords
Is the Therapeutic Mechanism of Repetitive Transcranial Magnetic Stimulation in Cognitive Dysfunctions of Depression Related to the Neuroinflammatory Processes in Depression?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.834425
Abstract: The lifetime prevalence of depression is reported to be >10%, and it is an important illness that causes various disabilities over a long period of life. Neuroinflammation process is often reported to be closely linked… read more here.
Keywords: magnetic stimulation; depression; repetitive transcranial; transcranial magnetic ... See more keywords