New diagnostic and therapeutic modalities in neuromuscular disorders in children.
Sign Up to like & getrecommendations! Published in 2021 at "Current problems in pediatric and adolescent health care"
DOI: 10.1016/j.cppeds.2021.101033
Abstract: Pediatric neuromuscular disorders are a diverse group of conditions that affect how muscle and nerve function. They involve the motor neurons, nerves, neuromuscular junction and muscles. Pathology of any of these regions leads to the… read more here.
Keywords: diagnostic therapeutic; neuromuscular disorders; therapeutic modalities; pediatric neuromuscular ... See more keywords
Therapeutic modalities and novel approaches in regenerative medicine for COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Antimicrobial Agents"
DOI: 10.1016/j.ijantimicag.2020.106208
Abstract: The recent coronavirus disease 2019 (COVID-19) outbreak around the world has an enormous impact on the global health burden, threatening the lives of many individuals, and has severe socio-economic consequences. Many pharmaceutical and biotechnology companies… read more here.
Keywords: medicine; modalities novel; novel approaches; therapeutic modalities ... See more keywords
Reimagining Druggability Using Chemoproteomic Platforms.
Sign Up to like & getrecommendations! Published in 2021 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.1c00065
Abstract: ConspectusOne of the biggest bottlenecks in modern drug discovery efforts is in tackling the undruggable proteome. Currently, over 85% of the proteome is still considered undruggable because most proteins lack well-defined binding pockets that can… read more here.
Keywords: chemoproteomic platforms; undruggable proteome; therapeutic modalities; reimagining druggability ... See more keywords
Drug Hunting at the Nexus of Medicinal Chemistry and Chemical Biology and the Discovery of Novel Therapeutic Modalities.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01491
Abstract: Small molecules designed to modulate protein function have been remarkably successful in advancing human health. As the frontiers of medicine and understanding of disease pathogenesis continue to expand, small molecule scientists must also pursue the… read more here.
Keywords: medicinal chemistry; therapeutic modalities; novel therapeutic; chemistry ... See more keywords
Intelligent Nanoplatform with Multi Therapeutic Modalities for Synergistic Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c01913
Abstract: Chemodynamic therapy (CDT) has attracted increasing attention in tumor treatment but is limited by insufficient endogenous H2O2. Moreover, it is challenging for monotherapy to achieve a satisfactory outcome due to tumor complexity. Herein, we developed… read more here.
Keywords: therapeutic modalities; multi therapeutic; therapy; intelligent nanoplatform ... See more keywords
Recent Advances in Therapeutic Modalities Against Breast Cancer-Related Lymphedema: Future Epigenetic Landscape.
Sign Up to like & getrecommendations! Published in 2023 at "Lymphatic research and biology"
DOI: 10.1089/lrb.2022.0016
Abstract: Background: Lymphedema is a significant postsurgical complication observed in the majority of breast cancer patients. These multifactorial etiopathogenesis have a significant role in the development of novel diagnostic/prognostic biomarkers and the development of novel therapies.… read more here.
Keywords: cancer related; related lymphedema; therapeutic modalities; breast cancer ... See more keywords
Striae Distensae: Preventative and Therapeutic Modalities to Improve Aesthetic Appearance
Sign Up to like & getrecommendations! Published in 2017 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000001079
Abstract: BACKGROUND Striae distensae (SD) are aesthetically troublesome to patients and therapeutically challenging. OBJECTIVE Herein, the authors comprehensively review the literature pertaining to the history, pathogenesis, clinical presentation, clinical rating scales, and laboratory, imaging, and histologic… read more here.
Keywords: distensae preventative; striae; therapeutic modalities; preventative therapeutic ... See more keywords
Current Therapeutic Modalities for the Management of Chronic Diabetic Wounds of the Foot
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Diabetes Research"
DOI: 10.1155/2023/1359537
Abstract: Impaired wound healing is common in patients with diabetes mellitus (DM). Different therapeutic modalities including wound debridement and dressing, transcutaneous electrical nerve stimulation (TENS), nanomedicine, shockwave therapy, hyperbaric (HBOT) and topical (TOT) oxygen therapy, and… read more here.
Keywords: management chronic; therapeutic modalities; current therapeutic; diabetic wounds ... See more keywords
Intelligent Nanomedicine Approaches Using Medical Gas-Mediated Multi-Therapeutic Modalities Against Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2022.3224
Abstract: The emerging area of gas-mediated cancer treatment has received widespread attention in the medical community. Featuring unique physical, chemical, and biological properties, nanomaterials can facilitate the delivery and controllable release of medicinal gases at tumor… read more here.
Keywords: gas; therapeutic modalities; gas mediated; nanomedicine approaches ... See more keywords
Recent progresses on pathophysiology, diagnosis, therapeutic modalities, and management of Non-alcoholic fatty liver disorder
Sign Up to like & getrecommendations! Published in 2023 at "Current Drug Therapy"
DOI: 10.2174/1574885518666230417111247
Abstract: Non-alcoholic fatty liver disease (NAFLD) is currently the utmost common chronic liver disorder that happens through all age groups and is identified to occur in 14%-30% of the general population, demonstrating a critical and grossing… read more here.
Keywords: alcoholic fatty; non alcoholic; therapeutic modalities; fatty liver ... See more keywords
Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13215506
Abstract: Simple Summary Cyclin-dependent kinases (CDKs) are rich and viable therapeutic targets for various cancers. The emergence of event-driven pharmacology as an alternative to occupancy-driven pharmacology has begun to address the challenges associated with selectively targeting… read more here.
Keywords: protein; protacs molecular; cyclin dependent; therapeutic modalities ... See more keywords