Development of a Paper-Based Luminescence Bioassay for Therapeutic Monitoring of Aminoglycosides: a Proof-of-Concept Study
Sign Up to like & getrecommendations! Published in 2019 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-019-03048-4
Abstract: Aminoglycosides are widely used antibiotics that bind to the bacterial 30S ribosomal subunit to inhibit translation. Owing to their adverse side effects and narrow therapeutic index, monitoring blood levels of aminoglycosides is important to maximize… read more here.
Keywords: paper based; paper; monitoring aminoglycosides; proof concept ... See more keywords
Dried plasma spots for therapeutic monitoring of amikacin: Validation of an UHPLC-MS/MS assay and pharmacokinetic application.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113201
Abstract: Amikacin (AMI) is an aminoglycoside antibiotic widely used in the treatment of severe infections caused by multi-resistant bacteria, with established exposition targets in therapeutic drug monitoring (TDM). The usual specimen for AMI concentration measurement is… read more here.
Keywords: dried plasma; plasma spots; spots therapeutic; ami ... See more keywords
Recent advances in electroanalytical methods for the therapeutic monitoring of antiepileptic drugs: A comprehensive review.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113394
Abstract: Frequency of seizures is often managed by a wide group of antiepileptic drugs. Regarding the pharmacokinetic variability, narrow targeted range, and difficulty of detecting signs of toxicity based on laboratory responses, therapeutic monitoring of antiepileptic… read more here.
Keywords: analysis; monitoring antiepileptic; recent advances; antiepileptic drugs ... See more keywords
Therapeutic monitoring of rivaroxaban in dogs using thromboelastography and prothrombin time
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DOI: 10.1111/jvim.15478
Abstract: Abstract Background The chromogenic anti‐Xa assay, the gold standard for monitoring the anti‐Xa effect of rivaroxaban, is not available as a cage‐side diagnostic test for use in a clinical setting. Hypothesis/Objectives To evaluate clinical modalities… read more here.
Keywords: point care; time; monitoring; monitoring rivaroxaban ... See more keywords