Allogeneic mesenchymal stromal cells: Novel therapeutic option for mutated FLNA‐associated respiratory failure in the pediatric setting
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24497
Abstract: Mesenchymal stromal cell (MSC)‐mediated therapeutic effects have been observed in the treatment of lung diseases. For the first time, this treatment was used as rescue therapy in a pediatric patient with a life‐threatening respiratory syndrome… read more here.
Keywords: mesenchymal stromal; stromal cells; therapeutic option; cells novel ... See more keywords
Steroids: A Therapeutic Option for COVID-19 Pneumonia Patients With ESRD?
Sign Up to like & getrecommendations! Published in 2020 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2020.05.031
Abstract: Figure 1. Evolution of oxygen flow over time. D0, day of initiation of corticosteroids. To the Editor: Alberici et al. proposed in a recent review some therapeutic approaches for patients with end-stage renal disease and… read more here.
Keywords: covid pneumonia; initiation; disease; covid ... See more keywords
Remdesivir as a possible therapeutic option for the COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Travel Medicine and Infectious Disease"
DOI: 10.1016/j.tmaid.2020.101615
Abstract: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive… read more here.
Keywords: version; remdesivir possible; option covid; therapeutic option ... See more keywords
Cariprazine as a therapeutic option for schizophrenia: a drug evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2020.1845315
Abstract: ABSTRACT Introduction: Schizophrenia is a very disabling condition that may result in a significant impairment of individual, professional, and social adjustments. Antipsychotics (APs), the first-line treatment for schizophrenia, in many cases modify the course of… read more here.
Keywords: schizophrenia; cariprazine therapeutic; therapeutic option; schizophrenia drug ... See more keywords
Lung Transplantation as a Therapeutic Option in Acute Respiratory Distress Syndrome
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DOI: 10.1097/tp.0000000000002004
Abstract: Background Lung transplantation (LTPL) is considered as a salvage therapeutic option in patients with end-stage lung disease. However, there is a lack of sufficient data on the use of LTPL in patients with acute respiratory… read more here.
Keywords: acute respiratory; therapeutic option; lung transplantation; lung ... See more keywords
Efficacy of tocilizumab in adult H syndrome: a promising therapeutic option
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Dermatology"
DOI: 10.1111/ijd.15649
Abstract: which was clearly lacking in GA lesions. Interestingly, individual red papules ultimately became flattened and pigmented, but new papules appeared along the border of the erythematous plaques and the lesions gradually enlarged, with central hyperpigmentation.… read more here.
Keywords: adult syndrome; efficacy tocilizumab; tocilizumab adult; syndrome promising ... See more keywords
Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007155
Abstract: Key Points • HDAC1 inhibition dampens IRF4 transcription through histone hyperacetylation, thereby reducing the expression of the survival mediator PIM2.• Simultaneous targeting of the intrinsic HDAC1-IRF4 axis plus externally activated PIM2 represents an efficient therapeutic… read more here.
Keywords: irf4 axis; therapeutic option; inhibition; hdac1 irf4 ... See more keywords
Lenvatinib as a Therapeutic Option in Unresectable Metastatic Pheochromocytoma and Paragangliomas
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvac044
Abstract: Abstract Context Metastatic pheochromocytomas and paragangliomas (mPPGL) are rare vascular neuroendocrine tumors that highly express vascular growth factors. Systemic treatment options in cases of unresectable multisite disease are limited. Multikinase inhibitors that inhibit angiogenesis, such… read more here.
Keywords: disease; paragangliomas; therapeutic option; treatment ... See more keywords
Montelukast: The New Therapeutic Option for the Treatment of Epilepsy
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Experimental Pharmacology"
DOI: 10.2147/jep.s277720
Abstract: Abstract Currently, there is no definitive cure for epilepsy. The available medications relieve symptoms and reduce seizure attacks. The major challenge with the available antiepileptic medication is safety and affordability. The repurposing of montelukast for… read more here.
Keywords: montelukast new; treatment; epilepsy; therapeutic option ... See more keywords
Mitochondrial Medicine: A Promising Therapeutic Option Against Various Neurodegenerative Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220830112408
Abstract: Abnormal mitochondrial morphology and metabolic dysfunction have been observed in many neurodegenerative disorders (NDDs). Mitochondrial dysfunction can be caused by aberrant mitochondrial DNA, mutant nuclear proteins that interact with mitochondria directly or indirectly, or unknown… read more here.
Keywords: promising therapeutic; mitochondrial medicine; therapeutic option; medicine ... See more keywords
Oligonucleotides—A Novel Promising Therapeutic Option for IBD
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.00314
Abstract: Inflammatory Bowel Diseases (IBD), whose denomination comprehends Crohn's Disease (CD) and Ulcerative Colitis (UC), are intestinal chronic diseases that often require lifelong medical therapy. In the last two decades monoclonal antibodies against the cytokine TNF… read more here.
Keywords: oligonucleotides novel; novel promising; efficacy; therapeutic option ... See more keywords