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Published in 2017 at "Amino Acids"
DOI: 10.1007/s00726-017-2447-9
Abstract: Polyamines are naturally occurring aliphatic compounds, particularly essential elements for biological functions. These compounds play a central role in regulating molecular pathways which are responsible for cellular proliferation, growth, and differentiation. Importantly, excessive polyamine catabolism…
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Keywords:
therapeutic perspectives;
inflammatory diseases;
inflammatory;
polyamines therapeutic ... See more keywords
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Published in 2019 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2019.05.001
Abstract: Lipodystrophy is a group of clinically heterogeneous, inherited or acquired, disorders characterized by complete or partial absence of subcutaneous adipose tissue that may occur simultaneously with the pathological, ectopic, accumulation of fat in other regions…
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Keywords:
therapeutic perspectives;
focus;
fatty liver;
lipodystrophy ... See more keywords
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Published in 2018 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2018.02.001
Abstract: Rheumatoid arthritis (RA) is a multifactorial immune disease exhibiting diverse clinical responses to specific therapeutic agents. Such heterogeneity reflects variable activation of signaling pathways. Consequently, RA physiopathology has been linked to many immune cells and…
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Keywords:
therapeutic perspectives;
perspectives interferons;
interferons plasmacytoid;
plasmacytoid dendritic ... See more keywords
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Published in 2020 at "CyTA - Journal of Food"
DOI: 10.1080/19476337.2020.1721562
Abstract: ABSTRACT In recent years, new avenue has been opened for extensive research and debate between Natural and artificial sweeteners. Stevia rebaudiana has emerged as a potent and remarkable substitute to artificial and calorie dense sweeteners.…
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Keywords:
therapeutic perspectives;
stevia rebaudiana;
nutritional therapeutic;
emerging sweetener ... See more keywords
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Published in 2022 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001055
Abstract: Purpose of review The pathophysiological understanding of cluster headache has evolved significantly over the past years. Although it is now well known that the trigeminovascular system, the parasympathetic system and the hypothalamus play important roles…
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Keywords:
headache;
mechanisms therapeutic;
therapeutic perspectives;
cluster headache ... See more keywords
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Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1035441
Abstract: Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of various disorders such as cancer,…
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Keywords:
updated pharmacological;
pharmacological review;
review;
diosgenin updated ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19112
Abstract: In this article, we review the origin and therapeutic perspectives of bladder cancer stem cells (BCSCs), which are integral to the initiation, high recurrence and chemoresistance of bladder cancer. BCSCs are heterogenous and originate from…
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Keywords:
therapeutic perspectives;
bladder cancer;
cancer;
stem cells ... See more keywords
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Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.15971
Abstract: Abstract Chemotherapy-induced peripheral neuropathy (CIPN) develops as a challenging nerve-damaging adverse effect of anticancer drugs used in chemotherapy. The disorder may require a chemotherapy dose reduction and a cessation of administration of chemotherapeutic drugs. Its…
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Keywords:
chemotherapy induced;
peripheral neuropathy;
perspectives chemotherapy;
therapeutic perspectives ... See more keywords
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.787141
Abstract: Background: CXCR (CXC Chemokine Receptor) is a complex of the immune-associated protein involved in tumor activation, invasion, migration, and angiogenesis through various chemical signals in the tumor microenvironment (TME). However, significant prognostic characteristics of CXCR…
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Keywords:
cxcr members;
value therapeutic;
risk;
therapeutic perspectives ... See more keywords
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Published in 2022 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.836367
Abstract: Exosomes are widely involved in a variety of physiological and pathological processes. These important roles are also hidden in the physiological processes related to bone. Chondrocytes, osteoblasts, synovial fibroblasts, and bone marrow mesenchymal stem cells…
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Keywords:
perspectives exosomes;
role;
osteoarthrosis;
induced osteoarthrosis ... See more keywords
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Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12030371
Abstract: Alzheimer’s and Parkinson’s diseases are the two most common forms of neurodegenerative diseases. The exact etiology of these disorders is not well known; however, environmental, molecular, and genetic influences play a major role in the…
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Keywords:
gallate egcg;
perspectives neuroprotection;
egcg new;
new therapeutic ... See more keywords