Hypoxia and its therapeutic possibilities in paediatric cancers
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DOI: 10.1038/s41416-020-01107-w
Abstract: In tumours, hypoxia—a condition in which the demand for oxygen is higher than its availability—is well known to be associated with reduced sensitivity to radiotherapy and chemotherapy, and with immunosuppression. The consequences of hypoxia on… read more here.
Keywords: therapeutic possibilities; hypoxia therapeutic; paediatric cancers; biology ... See more keywords
The Mystery of Diabetic Cardiomyopathy: From Early Concepts and Underlying Mechanisms to Novel Therapeutic Possibilities
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DOI: 10.3390/ijms22115973
Abstract: Diabetic patients are predisposed to diabetic cardiomyopathy, a specific form of cardiomyopathy which is characterized by the development of myocardial fibrosis, cardiomyocyte hypertrophy, and apoptosis that develops independently of concomitant macrovascular and microvascular diabetic complications.… read more here.
Keywords: therapeutic possibilities; early concepts; cardiomyopathy early; mystery diabetic ... See more keywords