Emerging therapeutic potentials of dual‐acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases
Sign Up to like & getrecommendations! Published in 2019 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201900177
Abstract: No drug has been approved to prevent neuronal cell loss in patients suffering from Parkinson's disease (PD) or Alzheimer's disease (AD); despite increased comprehension of the underlying molecular causes, therapies target cognitive functional improvement and… read more here.
Keywords: acting mao; emerging therapeutic; dual acting; drug ... See more keywords
Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7176
Abstract: Traditionally, herbal supplements have shown an exceptional potential of desirability for the prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound belongs to the isothiocyanate (ITC) group and is mainly found naturally in… read more here.
Keywords: recent patents; sulforaphane review; potentials advances; review therapeutic ... See more keywords
Nutritional and therapeutic potentials of rambutan fruit (Nephelium lappaceum L.) and the by-products: a review
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Food Measurement and Characterization"
DOI: 10.1007/s11694-018-9771-y
Abstract: The progressive development of functional foods and herbal medicine has enthused many researchers to explore novel plant sources. In this regard, the rambutan fruit (Nephelium lappaceum L.) appears to be a promising candidate primarily due… read more here.
Keywords: fruit nephelium; fruit; rambutan fruit; nephelium lappaceum ... See more keywords
The promising therapeutic potentials of ginsenosides mediated through p38 MAPK signaling inhibition
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e08354
Abstract: The p38 mitogen-activated protein kinases (p38 MAPK) is a 38kD polypeptide recognized as the target for many potential anti-inflammatory agents. Accumulating evidence indicates that p38 MAPK could perform many roles in human disease pathophysiology. Therefore,… read more here.
Keywords: p38 mapk; mapk signaling; therapeutic potentials; promising therapeutic ... See more keywords
Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials.
Sign Up to like & getrecommendations! Published in 2017 at "Human immunology"
DOI: 10.1016/j.humimm.2016.12.010
Abstract: Naïve CD4+ T cells are pleiotropically divided into various T helper (Th) cell subsets, according to their pivotal roles in the regulation of immune responses. The differentiation of Th9 cells, an interleukin (IL)-9 producing subset,… read more here.
Keywords: disorders pathogenesis; th9 cells; autoimmune disorders; therapeutic potentials ... See more keywords
The prognostic and therapeutic potentials of CTLA-4 in hematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2170781
Abstract: ABSTRACT Introduction Hematological Malignancies (HMs) are a group of progressive, difficult-to-treat, and highly recurrent diseases. A suppressed phenotype of the immune system is present in HMs and growing evidence indicates the role of Cytotoxic T… read more here.
Keywords: potentials ctla; hms; therapeutic potentials; prognostic therapeutic ... See more keywords
Stereotaxic-assisted gene therapy in Alzheimer’s and Parkinson’s diseases: therapeutic potentials and clinical frontiers
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2022.2056446
Abstract: ABSTRACT Introduction Alzheimer’s disease (AD) and Parkinson’s disease (PD) are neurodegenerative disorders causing cognitive deficits and motor difficulties in the elderly. Conventional treatments are mainly symptomatic with little ability to halt disease progression. Gene therapies… read more here.
Keywords: assisted gene; therapeutic potentials; gene therapy; gene ... See more keywords
Mitochondrial function in the heart: the insight into mechanisms and therapeutic potentials
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14431
Abstract: Mitochondrial dysfunction is considered as a crucial contributory factor in cardiac pathology. This has highlighted the therapeutic potential of targeting mitochondria to prevent or treat cardiac disease. Mitochondrial dysfunction is associated with aberrant electron transport… read more here.
Keywords: mechanisms therapeutic; mitochondrial function; insight mechanisms; therapeutic potentials ... See more keywords
Evaluating the Prognostic and Therapeutic Potentials of the Proteasome 26S Subunit, ATPase (PSMC) Family of Genes in Lung Adenocarcinoma: A Database Mining Approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.935286
Abstract: This study explored the prognostic and therapeutic potentials of multiple Proteasome 26S Subunit, ATPase (PSMC) family of genes (PSMC1-5) in lung adenocarcinoma (LUAD) diagnosis and treatment. All the PSMCs were found to be differentially expressed… read more here.
Keywords: atpase psmc; therapeutic potentials; prognostic therapeutic; subunit atpase ... See more keywords
Polyphenols: Chemoprevention and therapeutic potentials in hematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1008893
Abstract: Polyphenols are one of the largest plant-derived natural product and they play an important role in plants’ defense as well as in human health and disease. A number of them are pleiotropic molecules and have… read more here.
Keywords: chemoprevention therapeutic; polyphenols chemoprevention; therapeutic potentials; hematological malignancies ... See more keywords
An insight into novel therapeutic potentials of taxifolin
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1173855
Abstract: Taxifolin is a flavonoid compound, originally isolated from the bark of Douglas fir trees, which is often found in foods such as onions and olive oil, and is also used in commercial preparations, and has… read more here.
Keywords: system; novel therapeutic; therapeutic potentials; insight novel ... See more keywords