Ultrasensitive Profiling of Extracellular Vesicles by a Microbead- and Aptamer-Enhanced Thermophoretic Assay for Monitoring Therapeutic Responses.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c06434
Abstract: Longitudinal monitoring of therapeutic responses is essential for optimizing treatment strategies and improving outcomes in cancer patients. Profiling tumor-derived extracellular vesicles (tEVs) can provide critical information for effective and timely treatment monitoring. Here, we report… read more here.
Keywords: extracellular vesicles; monitoring therapeutic; microbead aptamer; monitoring ... See more keywords
SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer
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DOI: 10.1186/s13048-025-01758-4
Abstract: Solute carrier family 4 member 11 (SLC4A11) is involved in borate homeostasis, metabolism reprogramming, cell growth, and cell adhesion. However, the biological function of SLC4A11 in ovarian cancer (OC) is still unclear. This study explores… read more here.
Keywords: database; ovarian cancer; cell; therapeutic responses ... See more keywords
Prediction Model for Therapeutic Responses in Ovarian Cancer Patients using Paclitaxel-resistant Immune-related lncRNAs
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DOI: 10.2174/0109298673281438231217151129
Abstract: Background: Ovarian cancer (OC) is the deadliest malignant tumor in women with a poor prognosis due to drug resistance and lack of prediction tools for therapeutic responses to anti-cancer drugs. Objective: The objective of this… read more here.
Keywords: cancer; prediction; immune related; therapeutic responses ... See more keywords
Outcome prediction and evaluation by imaging the key elements of therapeutic responses to cancer immunotherapies using PET.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical design"
DOI: 10.2174/1381612825666190829150302
Abstract: Cancer immunotherapy (also known as immuno-oncology), a promising anti-cancer strategy by harnessing the body's own immune system against cancer, has emerged as the "fifth therapeutic pilla" in the field of cancer treatment since surgery, chemotherapy,… read more here.
Keywords: key elements; responses cancer; cancer; cancer immunotherapies ... See more keywords
Lipid metabolism characterization in gastric cancer identifies signatures to predict prognostic and therapeutic responses
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DOI: 10.3389/fgene.2022.959170
Abstract: Purpose: Increasing evidence has elucidated the significance of lipid metabolism in predicting therapeutic efficacy. Obviously, a systematic analysis of lipid metabolism characterizations of gastric cancer (GC) needs to be reported. Experimental design: Based on two… read more here.
Keywords: metabolism; metabolism characterization; lipid metabolism; therapeutic responses ... See more keywords
Current Understanding of Exosomal MicroRNAs in Glioma Immune Regulation and Therapeutic Responses
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DOI: 10.3389/fimmu.2021.813747
Abstract: Exosomes, the small extracellular vesicles, are released by multiple cell types, including tumor cells, and represent a novel avenue for intercellular communication via transferring diverse biomolecules. Recently, microRNAs (miRNAs) were demonstrated to be enclosed in… read more here.
Keywords: immune regulation; current understanding; therapeutic responses; glioma immune ... See more keywords
Monitoring Therapeutic Responses to Silicified Cancer Cell Immunotherapy Using PET/MRI in a Mouse Model of Disseminated Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810525
Abstract: Current imaging approaches used to monitor tumor progression can lack the ability to distinguish true progression from pseudoprogression. Simultaneous metabolic 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) and magnetic resonance imaging (MRI) offers new opportunities to… read more here.
Keywords: pet mri; monitoring therapeutic; immunotherapy; therapeutic responses ... See more keywords