Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108805
Abstract: Considerable genetic variation of N-methyl-d-aspartate receptors (NMDARs) has recently become apparent, with many hundreds of de novo variants identified through widely available clinical genetic testing. Individuals with GRIN variants present with neurological conditions such as… read more here.
Keywords: variation; therapeutic significance; clinical therapeutic; significance genetic ... See more keywords
Functional and Therapeutic Significance of Tumor-Associated Macrophages in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.781233
Abstract: The role of the tumor microenvironment (TME) in the progression of colorectal cancer (CRC) and its acquisition of resistance to treatment become the research hotspots. As an important component of TME, the tumor-associated macrophages (TAMs)… read more here.
Keywords: functional therapeutic; therapeutic significance; colorectal cancer; associated macrophages ... See more keywords