Therapeutic Suppression of Nonsense Mutation: An Emerging Target in Multiple Diseases and Thrombotic Disorders.
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DOI: 10.2174/1381612823666161122142950
Abstract: Nonsense mutations contribute to approximately 10-30% of the total human inherited diseases via disruption of protein translation. If any of the three termination codons (UGA, UAG and UAA) emerges prematurely [known as premature termination codon… read more here.
Keywords: nonsense mutation; thrombotic disorders; mutation; therapeutic suppression ... See more keywords