Exploration of the Therapeutic Time Window for Thrombectomy in Rat Models of Middle Cerebral Artery Ischemia‐Reperfusion
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DOI: 10.1002/brb3.70713
Abstract: To investigate the therapeutic time window of middle cerebral artery occlusion (MCAO) reperfusion in rats and the potential mechanism of injury beyond the time window. read more here.
Keywords: cerebral artery; time window; time; middle cerebral ... See more keywords
Therapeutic time window and regulation of autophagy by mild hypothermia after intracerebral hemorrhage in rats
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DOI: 10.1016/j.brainres.2018.04.005
Abstract: Although recent studies have shown that mild hypothermia has neuroprotective effects on intracerebral hemorrhage (ICH), the therapeutic time window of the therapy and the role of autophagy as a potential neuroprotective mechanism remain unclear. This… read more here.
Keywords: time window; therapeutic time; mild hypothermia; intracerebral hemorrhage ... See more keywords
Use of Machine Learning Algorithms to Predict the Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke Patients With an Extended Therapeutic Time Window
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DOI: 10.1097/rct.0000000000001341
Abstract: Objective The aim of this study was to evaluate the performance of machine learning (ML) algorithms in predicting the functional outcome of mechanical thrombectomy (MT) outside the 6-hour therapeutic time window in patients with acute… read more here.
Keywords: time window; learning algorithms; machine; machine learning ... See more keywords
Republished: Revisiting the therapeutic time window dogma: successful thrombectomy 6 days after stroke onset
Sign Up to like & getrecommendations! Published in 2018 at "Journal of NeuroInterventional Surgery"
DOI: 10.1136/neurintsurg-2018-014039.rep
Abstract: Stroke is the leading cause of serious long-term disability in the USA. Recent clinical trials, DAWN and DEFUSE 3, have expanded the endovascular therapeutic time window which has been adopted by the American Heart Association… read more here.
Keywords: time window; therapeutic time; time; thrombectomy days ... See more keywords
Abstract WP220: Assessing the Therapeutic Time Window for Tranexamic Acid in Intracerebral Hemorrhage – A Systematic Review and Meta-analysis
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DOI: 10.1161/str.56.suppl_1.wp220
Abstract: Background: Several studies have shown that tranexamic acid (TXA), an anti-fibrinolytic agent, may reduce hematoma expansion (HE) in intracerebral hemorrhage (ICH), but its therapeutic time window is unclear. We analyzed the efficacy and safety of… read more here.
Keywords: tranexamic acid; txa; therapeutic time; intracerebral hemorrhage ... See more keywords
The Importance of Therapeutic Time Window in the Treatment of Traumatic Brain Injury
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DOI: 10.3389/fnins.2019.00007
Abstract: Traumatic brain injury (TBI) is a major cause of death and disability. Despite its importance in public health, there are presently no drugs to treat TBI. Many reasons underlie why drugs have failed clinical trials,… read more here.
Keywords: time window; therapeutic time; time; tbi ... See more keywords