Artificial miRNAs as therapeutic tools: Challenges and opportunities
Sign Up to like & getrecommendations! Published in 2021 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1640
Abstract: RNA interference (RNAi) technology has been used for almost two decades to study gene functions and in therapeutic approaches. It uses cellular machinery and small, designed RNAs in the form of synthetic small interfering RNAs… read more here.
Keywords: challenges opportunities; artificial mirnas; pri mirna; therapeutic tools ... See more keywords
Innovative approaches in transforming microRNAs into therapeutic tools
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1768
Abstract: MicroRNA (miRNA) is regarded as a prominent genetic regulator, as it can fine‐tune an entire biological pathway by targeting multiple target genes. This characteristic makes miRNAs promising therapeutic tools to reinstate cell functions that are… read more here.
Keywords: innovative approaches; therapeutic tools; micrornas therapeutic; approaches transforming ... See more keywords
A narrative literature review: the application of video games as therapeutic tools for psychological therapy
Sign Up to like & getrecommendations! Published in 2021 at "Australasian Psychiatry"
DOI: 10.1177/10398562211022751
Abstract: Objectives: Video games (games played by electronically manipulating images produced by a computer programme on a screen) are being developed with a specific focus on treating mental health. This narrative review briefly discusses the history… read more here.
Keywords: therapeutic tools; games therapeutic; application video; video games ... See more keywords
Inteins as Drug Targets and Therapeutic Tools
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.821146
Abstract: Multidrug-resistant pathogens are of significant concern in recent years. Hence new antifungal and anti-bacterial drug targets are urgently needed before the situation goes beyond control. Inteins are polypeptides that self-splice from exteins without the need… read more here.
Keywords: therapeutic tools; drug targets; drug; targets therapeutic ... See more keywords
The Role of miRNAs as Therapeutic Tools in Sickle Cell Disease
Sign Up to like & getrecommendations! Published in 2021 at "Medicina"
DOI: 10.3390/medicina57101106
Abstract: Background and Objectives: Sickle cell disorder (SCD) is a paradigmatic example of a complex monogenic disorder. SCD is characterized by the production of abnormal hemoglobin, primarily in the deoxygenated state, which makes erythrocytes susceptible to… read more here.
Keywords: sickle cell; role mirnas; tools sickle; therapeutic tools ... See more keywords
miRNAs as Therapeutic Tools and Biomarkers for Prostate Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13030380
Abstract: Prostate cancer (PCa) is the fifth cause of tumor-related deaths in man worldwide. Despite the considerable improvement in the clinical management of PCa, several limitations emerged both in the screening for early diagnosis and in… read more here.
Keywords: prostate cancer; therapeutic tools; cancer; biomarkers prostate ... See more keywords
CRISPR therapeutic tools for complex genetic disorders and cancer (Review)
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Oncology"
DOI: 10.3892/ijo.2018.4434
Abstract: One of the fundamental discoveries in the field of biology is the ability to modulate the genome and to monitor the functional outputs derived from genomic alterations. In order to unravel new therapeutic options, scientists… read more here.
Keywords: crispr therapeutic; crispr system; therapeutic tools; biology ... See more keywords