Implementing Pre-Therapeutic UGT1A1 Genotyping in Clinical Practice: A Real-Life Study
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DOI: 10.3390/jpm12020204
Abstract: Current guidelines recommend pre-therapeutic UGT1A1 genotyping to guide irinotecan dosing, but the usefulness of this approach remains to be clarified. In 247 patients with advanced gastrointestinal cancers undergoing irinotecan-based chemotherapy, we prospectively performed UGT1A1*28 genotyping… read more here.
Keywords: ugt1a1 genotyping; implementing pre; severe neutropenia; therapeutic ugt1a1 ... See more keywords