High-grade glioma associated immunosuppression does not prevent immune responses induced by therapeutic vaccines in combination with Treg depletion
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-018-2214-0
Abstract: High-grade gliomas (HGG) exert systemic immunosuppression, which is of particular importance as immunotherapeutic strategies such as therapeutic vaccines are increasingly used to treat HGGs. In a first cohort of 61 HGG patients we evaluated a… read more here.
Keywords: treg depletion; high grade; immune responses; hgg patients ... See more keywords
Physiopathology and effectiveness of therapeutic vaccines against human papillomavirus
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-15441-w
Abstract: Human papillomavirus (HPV) is a well-known sexually transmitted disorder globally. Human papillomavirus (HPV) is the 3rd most common cancer that causes cervical carcinoma, and globally it accounts for 275,000 deaths every year. The load of… read more here.
Keywords: hpv associated; based vaccines; hpv; human papillomavirus ... See more keywords
Design of therapeutic vaccines as a novel antibody therapy for cardiovascular diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2017.01.010
Abstract: Vaccines are primarily used worldwide as a preventive medicine for infectious diseases and have recently been applied to cancer. We and others have developed therapeutic vaccines designed for cardiovascular diseases that are notably different from… read more here.
Keywords: antibody therapy; antibody; cardiovascular diseases; cancer ... See more keywords
Therapeutic vaccines for allergic disease
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DOI: 10.1038/s41541-017-0014-8
Abstract: Allergic diseases are highly prevalent worldwide and affect all age groups, contributing to a high personal and socioeconomic burden. Treatment with an “allergy vaccine” or allergen immunotherapy aims to provide long-lasting benefits by inducing unresponsiveness… read more here.
Keywords: allergic disease; allergen immunotherapy; disease; vaccines allergic ... See more keywords
Safety, efficacy and immunogenicity of therapeutic vaccines in the treatment of patients with high-grade cervical intraepithelial neoplasia associated with human papillomavirus: a systematic review protocol
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DOI: 10.1136/bmjopen-2018-026975
Abstract: Introduction Eighty per cent of the sexually active population will get human papillomavirus (HPV) infection, which is the most prevalent sexually transmitted disease worldwide. Persistence of high-grade HPV infection may evolve to a cervical intraepithelial… read more here.
Keywords: efficacy immunogenicity; immunogenicity therapeutic; high grade; safety efficacy ... See more keywords
New Approaches to Dendritic Cell-Based Therapeutic Vaccines Against HIV-1 Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.719664
Abstract: Due to the success of combined antiretroviral therapy (cART) in recent years, the pathological outcome of Human Immunodeficiency Virus type 1 (HIV-1) infection has improved substantially, achieving undetectable viral loads in most cases. Nevertheless, the… read more here.
Keywords: cell; approaches dendritic; new approaches; infection ... See more keywords
Characteristics of clinical trials for non-small cell lung cancer therapeutic vaccines registered on ClinicalTrials.gov
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DOI: 10.3389/fimmu.2022.936667
Abstract: Background Even after complete surgical treatment or chemotherapy, Non-Small Cell Lung Cancer (NSCLC) patients are also at substantial risk for recurrence and spread trend. Therapeutic cancer vaccination could increase the anti-tumor immune response and prevent… read more here.
Keywords: non small; clinical trials; small cell; clinicaltrials gov ... See more keywords
Recent Progress on Therapeutic Vaccines for Breast Cancer
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DOI: 10.3389/fonc.2022.905832
Abstract: Breast cancer remains the most frequently diagnosed malignancy worldwide. Advanced breast cancer is still an incurable disease mainly because of its heterogeneity and limited immunogenicity. The great success of cancer immunotherapy is paving the way… read more here.
Keywords: recent progress; vaccines breast; breast cancer; cancer ... See more keywords
Therapeutic Vaccines for HPV-Associated Oropharyngeal and Cervical Cancer: The Next De-Intensification Strategy?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158395
Abstract: The rise in human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) has prompted a quest for further understanding of the role of high-risk HPV in tumor initiation and progression. Patients with HPV-positive OPSCC (HPV+ OPSCC)… read more here.
Keywords: cervical cancer; intensification; hpv associated; associated oropharyngeal ... See more keywords