Targeted Therapeutics for Transthyretin amyloid cardiomyopathy: Time to Move Forward
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DOI: 10.1016/j.cardfail.2019.07.080
Abstract: Introduction Deposition of wild type or mutant transthyretin (TTR) amyloid fibrils causes TTR cardiac amyloidosis (ATTR-CA). Targeted therapeutics (TT) for ATTR-CA include TTR stabilizers (tafamidis, dilfunisal) and oligonucleotide drugs (Revusiran, Patisiran and Inotersen).TTR stabilizers prevent… read more here.
Keywords: targeted therapeutics; patients attr; therapeutics transthyretin; cause mortality ... See more keywords