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Published in 2020 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s258594
Abstract: Abstract Severe refractory asthma (SRA) still has a high economic and social impact, including a reduction in quality of life (QoL), productivity, a greater risk of exacerbations and emergency department (ED) visits. Another major issue…
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Keywords:
eosinophilic asthma;
biological drugs;
review;
therapies severe ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119563
Abstract: Currently, three classes of monoclonal antibodies targeting type 2 inflammation pathways are available in Italy for the treatment of severe asthma: anti-IgE (Omalizumab), anti-IL-5/anti-IL-5Rα (Mepolizumab and Benralizumab), and anti-IL-4Rα (Dupilumab). Numerous randomized controlled trials (RCTs)…
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Keywords:
biological therapies;
therapies severe;
anti;
treatment ... See more keywords