Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics.
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DOI: 10.2217/fmb-2018-0110
Abstract: AIM To evaluate the activity of the 2-aminothiazole UPAR-174 following an unexplored approach: targeting Mycobacterium tuberculosis with lipophilic compounds that present antituberculosis and efflux inhibitory activity. METHODS Antituberculosis activity was assessed against replicating, nonreplicating and… read more here.
Keywords: targeting mycobacterium; tuberculosis; therapies tuberculosis; adjuvant therapies ... See more keywords