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   Articles with "therapy" as a keyword



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A Measured Approach to Vena Cava Filter Use-Respect Rather Than Regret.

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recommendations! Published in 2017 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2016.3882

Abstract: Is there enough evidence to support the use of inferior vena cava filters?—Yes. There is a strong effort among many physicians to avoid the use of inferior vena cava filters (IVCFs) in the treatment of… read more here.

Keywords: therapy; benefit; vena cava; use ... See more keywords
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Perspective on Trends in Statin Use.

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recommendations! Published in 2017 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2016.4710

Abstract: Since their introduction in the 1990s, statins have become the most common class of prescription medications in the United States.1 Statins work by blocking the critical pathway in the synthesis of cholesterol in the liver.… read more here.

Keywords: statin use; use; cardiology; cholesterol ... See more keywords
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Association of Fenofibrate Therapy With Long-term Cardiovascular Risk in Statin-Treated Patients With Type 2 Diabetes

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recommendations! Published in 2017 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2016.4828

Abstract: Importance Patients with type 2 diabetes are at high risk of cardiovascular disease (CVD) in part owing to hypertriglyceridemia and low high-density lipoprotein cholesterol. It is unknown whether adding triglyceride-lowering treatment to statin reduces this… read more here.

Keywords: risk; therapy; patients type; study ... See more keywords
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Effect of Trimetazidine Dihydrochloride Therapy on Exercise Capacity in Patients With Nonobstructive Hypertrophic Cardiomyopathy: A Randomized Clinical Trial

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recommendations! Published in 2019 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2018.4847

Abstract: Importance Hypertrophic cardiomyopathy causes limiting symptoms in patients, mediated partly through inefficient myocardial energy use. There is conflicting evidence for therapy with inhibitors of myocardial fatty acid metabolism in patients with nonobstructive hypertrophic cardiomyopathy. Objective… read more here.

Keywords: therapy; nonobstructive hypertrophic; exercise capacity; hypertrophic cardiomyopathy ... See more keywords
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Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial.

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recommendations! Published in 2020 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2020.0640

Abstract: Importance Despite evidence that guideline-directed medical therapy (GDMT) improves outcomes in patients with heart failure (HF) and reduced ejection fraction, many patients are undertreated. The Guiding Evidence-Based Therapy Using Biomarker Intensified Treatment (GUIDE-IT) trial tested… read more here.

Keywords: trial; guideline directed; analysis; medical therapy ... See more keywords
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Association of Low-Dose Triple Combination Therapy vs Usual Care With Time at Target Blood Pressure: A Secondary Analysis of the TRIUMPH Randomized Clinical Trial.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.0471

Abstract: Importance Cumulative exposure to high blood pressure (BP) is an adverse prognostic marker. Assessments of BP control over time, such as time at target, have been developed but assessments of the effects of BP-lowering interventions… read more here.

Keywords: usual care; time; time target; therapy ... See more keywords
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Rivaroxaban Monotherapy vs Combination Therapy With Antiplatelets on Total Thrombotic and Bleeding Events in Atrial Fibrillation With Stable Coronary Artery Disease: A Post Hoc Secondary Analysis of the AFIRE Trial.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.1561

Abstract: Importance Appropriate regimens of antithrombotic therapy for patients with atrial fibrillation (AF) and coronary artery disease (CAD) have not yet been established. Objective To compare the total number of thrombotic and/or bleeding events between rivaroxaban… read more here.

Keywords: rivaroxaban monotherapy; therapy; monotherapy; combination therapy ... See more keywords
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Contemporary Use of Sodium-Glucose Cotransporter-2 Inhibitor Therapy Among Patients Hospitalized for Heart Failure With Reduced Ejection Fraction in the US: The Get With The Guidelines-Heart Failure Registry.

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recommendations! Published in 2023 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2023.1266

Abstract: Importance Clinical guidelines for patients with heart failure with reduced ejection fraction (HFrEF) strongly recommend treatment with a sodium-glucose cotransporter-2 inhibitor (SGLT2i) to reduce cardiovascular mortality or HF hospitalization. Nationwide adoption of SGLT2i for HFrEF… read more here.

Keywords: heart failure; inhibitor; therapy; heart ... See more keywords
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Effect of Expedited Microneedle-Assisted Photodynamic Therapy for Field Treatment of Actinic Keratoses: A Randomized Clinical Trial

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recommendations! Published in 2017 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2017.0849

Abstract: Importance Photodynamic therapy (PDT) is an effective and cosmetically favorable treatment modality for actinic keratoses (AKs). However, prolonged incubation times and pain associated with treatment are burdensome to the patient and a hindrance to widespread… read more here.

Keywords: photodynamic therapy; trial; dermatology; treatment ... See more keywords
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Association of Anti-Programmed Cell Death 1 Antibody Treatment With Risk of Recurrence of Toxic Effects After Immune-Related Adverse Events of Ipilimumab in Patients With Metastatic Melanoma.

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recommendations! Published in 2020 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2020.2149

Abstract: Importance Since 2011, many patients with metastatic melanoma have been treated with ipilimumab therapy and have developed severe immune-related adverse events (AEs). Because several immune therapies are now available to treat metastatic melanoma, a better… read more here.

Keywords: therapy; related aes; immune related; metastatic melanoma ... See more keywords
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Association of Cutaneous Immune-Related Adverse Events With Increased Survival in Patients Treated With Anti-Programmed Cell Death 1 and Anti-Programmed Cell Death Ligand 1 Therapy.

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recommendations! Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2021.5476

Abstract: Importance Despite the efficacy of immune checkpoint inhibitors (ICIs), cutaneous immune-related adverse events (cirAEs) occur in 20% to 40% of all treated patients. To our knowledge, little is known about the predictive value of these… read more here.

Keywords: cell death; therapy; programmed cell; anti programmed ... See more keywords