Impact of age, antiretroviral therapy, and cancer on epigenetic aging in people living with HIV
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5809
Abstract: Premature aging has been identified as a global risk factor for cancer. Causes of premature aging are multifactorial, including inflammation, infection, chronic stress, and lifestyle factors. read more here.
Keywords: therapy cancer; age antiretroviral; antiretroviral therapy; cancer epigenetic ... See more keywords
Amphiphilic Cationic Phthalocyanines for Photodynamic Therapy of Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202200133
Abstract: Effective interaction with biomembranes is essential for activity of photosensitizers; however, majority of them are highly charged symmetrical species. Amphiphilic cationic phthalocyanines differing in bulkiness of substitution on lipophilic part (-H, -SMe, -StBu) were therefore… read more here.
Keywords: therapy cancer; cationic phthalocyanines; phthalocyanines photodynamic; amphiphilic cationic ... See more keywords
Placebo therapy for cancer-related pain: an alternative to psychotherapy or health misinformation?
Sign Up to like & getrecommendations! Published in 2019 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-019-05010-w
Abstract: First, most of the practices referred to in this review (e.g. acupuncture, healing touch, yoga, tai chi/qigong, mind-body therapies...) are neither rational nor supported by evidence for any effectiveness on relevant clinical outcomes.(2) Belief, however… read more here.
Keywords: placebo therapy; pain alternative; therapy cancer; cancer related ... See more keywords
Targeted Degradation of KRASG12D as Potential Therapy in Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.3c00111
Abstract: Selective proteolysis represents a cutting-edge therapeutic approach that is garnering global interest due to its capacity to eradicate pathogenic biomolecules within cellular environments. For instance, the PROTAC technology brings the ubiquitin proteasome system degradation machinery… read more here.
Keywords: potential therapy; therapy cancer; krasg12d potential; targeted degradation ... See more keywords
Indocyanine-type Infrared-820 Encapsulated Polymeric Nanoparticle-Assisted Photothermal Therapy of Cancer
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DOI: 10.1021/acsomega.2c00306
Abstract: Organic small-molecule photosensitizers are well-characterized and known for the light-responsive treatment modality including photodynamic therapy. Compared with ultraviolet–visible (UV–vis) light used in conventional photodynamic therapy with organic photosensitizers, near-infrared (NIR) light from 700 to 900… read more here.
Keywords: 820 loaded; photothermal therapy; therapy cancer; therapy ... See more keywords
Photodynamic Therapy for Cancer: What's Past is Prologue
Sign Up to like & getrecommendations! Published in 2019 at "Photochemistry and Photobiology"
DOI: 10.1111/php.13190
Abstract: Thomas J Dougherty from Roswell Park Cancer Center played a major role in the progress of photodynamic therapy (PDT) from a laboratory science into a real‐world clinical therapy to treat patients with cancer. Nevertheless over… read more here.
Keywords: therapy; photodynamic therapy; past prologue; therapy cancer ... See more keywords
Smart DNA nanogel coated polydopamine nanoparticle with high drug loading for chemo-photothermal therapy of cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Biointerphases"
DOI: 10.1116/6.0002170
Abstract: A smart deoxyribose nucleic acid nanogel coated polydopamine nanosphere hybrid was designed for chemo-photothermal therapy of cancer. The nanohybrid showed good colloid stability, narrow size distribution, high drug loading, good biocompatibility, and high photothermal conversion… read more here.
Keywords: photothermal therapy; therapy cancer; nanogel coated; coated polydopamine ... See more keywords
CAR-T Cell Therapy in Cancer: Tribulations and Road Ahead
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/1924379
Abstract: Chimeric antigen receptor- (CAR-) T cell therapy is one of the most recent innovative immunotherapies and is rapidly evolving. Like other technologies, CAR-T cell therapy has undergone a long development process, and persistent explorations of… read more here.
Keywords: cell therapy; car cell; car; therapy cancer ... See more keywords
Research Trends of Acupuncture Therapy on Cancer Over the Past Two Decades: A Bibliometric Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Integrative Cancer Therapies"
DOI: 10.1177/1534735420959442
Abstract: Purpose: Acupuncture has been used for managing cancer-related symptoms. However, there are still few studies concerning the overall trends in acupuncture therapy on cancer based on bibliometric analysis. This study aims to demonstrate the current… read more here.
Keywords: medicine; research; therapy cancer; analysis ... See more keywords
Current insights and future perspectives of hypoxia-inducible factor-targeted therapy in cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2017-0167
Abstract: Abstract Hypoxia-inducible factors (HIFs) are transcription factors that are expressed in the hypoxic tumor microenvironment. They are involved in the cellular adaptations by improving the metabolism of glucose and enhance the expression of vascular endothelial… read more here.
Keywords: hif; therapy cancer; targeted therapy; factor ... See more keywords
Polyphenols as the Potential Disease-modifying Therapy in Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520622666220201105204
Abstract: BACKGROUND Disease-modifying therapy in cancer can be defined as long-term treatment that has a beneficial outcome on the course of cancer, affecting the underlying pathophysiology. The anticancer potential of polyphenols is widely studied. However, there… read more here.
Keywords: therapy cancer; disease; modifying therapy; disease modifying ... See more keywords